Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT01409304 | Effectiveness of Deep Transcranial Magnetic Stimulation in Depression | PHASE2 | COMPLETED | 18 | — | — | Oct 1, 2011 | Dec 1, 2012 | Jan 18, 2013 | 1 | Canada |
Response to treatment is defined as a ≥ 50% reduction in the scores of the HAM-D21. Remission is defined as a HAM-D21 score ≤ 9.
| Name | Type | Description |
|---|---|---|
| Deep Transcranial Magnetic Stimulation (DTMS) | DEVICE | DTMS will be administered according to the following parameters: 18 Hz in 84 trains of 2 seconds duration, with 20 seconds inter-train interval (3,024 pulses per session) at 120% of the resting motor threshold. |
Inclusion Criteria: * Presence of a current major depressive disorder (according to the DSM-IV-TR) that has not improved after ≥ 1 but ≤ 5 adequate antidepressant trial(s) in the current episode * Baseline score ≥ 15 on the QIDS-C * Stable medication regimen (\> 4 weeks) Exclusion Criteria: * Psy...