Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Also known as Nifedipine (Adalat CR, BAYA1040) 80mg OD
Nifedipine OD · 1 trial · 1 indication
Changes of sitting SBP and DBP (trough values) from baseline (ie \[trough BP at the end of each period during the double-blind treatment period\] minus \[trough BP at the end of the baseline treatment period\])
| Arm | Type | Description |
|---|---|---|
| Nifedipine (Adalat CR, BAYA1040) 40 mg OD | ACTIVE_COMPARATOR | Nifedipine (Adalat CR, BAYA1040) 40 milligram (mg) once daily (OD) in the morning |
| Nifedipine (Adalat CR, BAYA1040) 40 mg BID | EXPERIMENTAL | Nifedipine (Adalat CR, BAYA1040) 40 milligram (mg) twice daily (BID). 40 mg in the morning and 40 mg in the evening |
| Nifedipine (Adalat CR, BAYA1040) 80 mg OD | EXPERIMENTAL | Nifedipine (Adalat CR, BAYA1040) 80 milligram (mg) once daily (OD) in the morning |
| Name | Type | Description |
|---|---|---|
| Nifedipine (Adalat CR, BAYA1040) 80mg OD | DRUG | Nifedipine (Adalat CR, BAYA1040) 80 milligram (mg) once daily (OD) in the morning |
| Nifedipine (Adalat CR, BAYA1040) 40mg BID | DRUG | Nifedipine (Adalat CR, BAYA1040) 40 milligram (mg) twice daily (BID). 40 mg in the morning and 40 mg in the evening |
| Nifedipine (Adalat CR, BAYA1040) 40mg OD | DRUG | Nifedipine (Adalat CR, BAYA1040) 40 milligram (mg) once daily (OD) in the morning |
Inclusion Criteria: * Male and female * 20 years or older and less than 75 years * Outpatient * Untreated or treated patients with antihypertensive agents whose blood pressure (BP) in sitting position at entry (Visit 1) is as follows. * Untreated patients: systolic blood pressure (SBP) \>= 160mm...