Recent Updates
Recently added Catalysts

CAM-3001

Phase 1

Rheumatoid Arthritis | Small molecule | Immunology |AstraZeneca PLC|Last Updated: Jul 20, 2012

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment38

FDA Designations

No designations recorded

Clinical trial landscape

CAM-3001 · 1 trial · 1 indication

Phase 1 1
NCT00771420A Single Dose Study of the CAM-3001 in Patients With Rheumatoid ArthritisRheumatoid Arthritis
COMPLETED38 Analytics
PHASE1COMPLETED
A Single Dose Study of the CAM-3001 in Patients With Rheumatoid Arthritis
Rheumatoid ArthritisUnlock trial analytics

Study Endpoints

Primary Endpoints

Incidence and severity of adverse events • Changes in vital signs, ECG, lung function tests and clinical laboratory values
End of study

Secondary Endpoints

Pharmacokinetic parameters of CAM-3001 will be calculated and tabulated descriptively for each dose group:
Day 28 post infusion
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1ACTIVE_COMPARATOR0.01mg/kg and 0.03mg/kg CAM-3001
2ACTIVE_COMPARATOR0.1mg/kg CAM-3001
3ACTIVE_COMPARATOR0.3mg/kg CAM-3001
4ACTIVE_COMPARATOR1.0mg/kg CAM-3001
5ACTIVE_COMPARATOR3.0mg/kgCAM-3001
6ACTIVE_COMPARATOR10.0mg/kg CAM-3001
7PLACEBO_COMPARATORPlacebo

Interventions

NameTypeDescription
CAM-3001DRUGA single patient shall be dosed with a dose of 0.01mg/kg of CAM-3001 followed no sooner than 24 hours later by a second patient at a dose of 0.03mg/kg.
PlaceboOTHERActive: Placebo 5:1 for arms 2-6
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to 70 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Signed and dated informed consent, prior to any study related procedures * Male and female patients aged 18-70 years at the screening visit * Use of an appropriate method of contraception * A diagnosis of adult onset rheumatoid arthritis of at least 6 months duration as define...

Countries:Germany
Unlock Eligibility Criteria

Frequently asked questions about CAM-3001

What is CAM-3001 used for in rheumatoid arthritis?

CAM-3001 is an investigational small molecule being developed for the treatment of rheumatoid arthritis. It is currently in Phase 1 clinical development, meaning it has not yet been approved and is still being studied for safety and efficacy in patients.

Who makes CAM-3001?

CAM-3001 is being developed by AstraZeneca PLC, a biopharmaceutical company listed on the stock exchange under the ticker symbol AZN. The company is conducting clinical trials to evaluate the drug's potential in treating rheumatoid arthritis.

What phase is CAM-3001 in?

CAM-3001 is in Phase 1 clinical development. It is an investigational drug, not yet approved by regulatory authorities. A Phase 1 trial has been completed to assess its safety and tolerability in patients with rheumatoid arthritis.

What clinical trials is CAM-3001 in?

CAM-3001 has one completed clinical trial, identified as NCT00771420, titled 'A Single Dose Study of the CAM-3001 in Patients With Rheumatoid Arthritis.' This Phase 1 study enrolled 38 participants in Germany and was placebo-controlled and double-blind.

Is CAM-3001 FDA approved?

CAM-3001 is not FDA approved. It is an investigational drug currently in Phase 1 clinical development for rheumatoid arthritis. The drug has completed a Phase 1 trial, but further studies are needed before it can be considered for regulatory approval.

What is CAM-3001?

CAM-3001 is an investigational small molecule being developed by AstraZeneca PLC for the treatment of rheumatoid arthritis. It is currently in Phase 1 clinical development, with one completed trial (NCT00771420) that enrolled 38 patients in Germany.