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RF ablation

Phase 2

Non Small Cell Lung Cancer | Unknown | Oncology |AngioDynamics, Inc.|Trials Updated: Jun 5, 2008

RF ablation development status

Highest phase Phase 2
Registered trials 1 across 1 sponsor since Jul 2011

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment106

FDA Designations

No designations recorded

RF ablation clinical trials

RF ablation · 1 trial · 2 indications

Phase 2 1
NCT00690703Radiofrequency Ablation of Pulmonary Tumors Response EvaluationNon Small Cell Lung Cancer
COMPLETED106 Analytics
PHASE2COMPLETED
Radiofrequency Ablation of Pulmonary Tumors Response Evaluation
Non Small Cell Lung CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

technical success
immediate
complications
30 days
pulmonary function
2 years
tumor response
1 years

Secondary Endpoints

overall survival
2 years
cancer-specific survival
2 years
quality of life
2 years
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTALTreatment

Interventions

NameTypeDescription
RF ablation (Rita Medical Systems Model 1500x)DEVICEcomputed tomography-guided RF ablation with an expandable electrode needle
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites7

Inclusion Criteria: 1. adult (\> 18 years) male or female patient 2. patient has biopsy-proven NSCLC or lung metastasis 3. patient has been rejected for surgery and has been considered unfit for radiation therapy or chemotherapy 4. patient has as many as 3 tumors per lung, each 3.5 cm or smaller in...

Countries:United StatesAustraliaGermanyItalyUnited Kingdom
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Competitive Landscape -Non-Small Cell Lung Cancer 541 trials (matched to "Non Small Cell Lung Cancer")

Top 20 of 90 competitors

CompanyTickerTrialsLead PhaseDrugs
Merck & Co., Inc.MRK37PHASE3Pembrolizumab, Olaparib, Sacituzumab tirumotecan, Intismeran autogene, Pembrolizumab Berahyaluronidase alfa
Revolution Medicines, Inc.RVMD9PHASE3Daraxonrasib, Zoldonrasib, Elironrasib, RMC-5127
Eli Lilly and CompanyLLY18PHASE3Selpercatinib, Pemetrexed, Abemaciclib, Olomorasib, LY3537982
AbbVie, Inc.ABBV12PHASE3ABBV-1480, Telisotuzumab vedotin, Telisotuzumab Adizutecan, Livmoniplimab, Budigalimab
AstraZeneca PLCAZN68PHASE3Datopotamab deruxtecan, Durvalumab, Oleclumab, Monalizumab, Tremelimumab
Gilead Sciences, Inc.GILD7PHASE3Sacituzumab govitecan, Zimberelimab, Domvanalimab, Etrumadenant, TUB-040- Dose escalation
Bristol-Myers Squibb CompanyBMY24PHASE3Repotrectinib, Nivolumab, Pumitamig, Relatlimab, Adagrasib
Johnson & JohnsonJNJ19PHASE3Lazertinib, Amivantamab, JNJ-90301900, JNJ-86974680, Cetrelimab
BioNTech SE Sponsored ADRBNTX7PHASE3Gotistobart, Pumitamig, BNT326, BNT116, BNT324
Pfizer Inc.PFE20PHASE3Lorlatinib, Crizotinib, Avelumab, Talazoparib, Axitinib
Amgen Inc.AMGN4PHASE3ABP 234, Sotorasib, Anvumetostat
Novartis AG Sponsored ADRNVS12PHASE3Opnurasib, TNO155, DKY709, Spartalizumab, trametinib
GSK plc Sponsored ADRGSK3PHASE3Dostarlimab, Belrestotug, Nelistotug, Cobolimab
ArriVent BioPharma, Inc.AVBP9PHASE3Firmonertinib
Summit Therapeutics IncSMMT2PHASE3Ivonescimab
Nuvation Bio, Inc. Class ANUVB4PHASE3Taletrectinib
Genmab A/S Sponsored ADRGMAB4PHASE3Acasunlimab, Rina-S, GEN1042
Regeneron Pharmaceuticals, Inc.REGN7PHASE2Cemiplimab, Marlotamig, Fianlimab, REGN5093
Nuvalent, Inc. Class ANUVL1PHASE3Neladalkib
BeOne Medicines Ltd. Sponsored ADRONC7PHASE3Tislelizumab, BGB-A445, LBL-007, BGB-15025, BGB-43395
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Frequently asked questions about RF ablation

What is RF ablation used for in Non Small Cell Lung Cancer?

RF ablation is a minimally invasive procedure being studied for the treatment of Non Small Cell Lung Cancer and pulmonary metastases. It uses radiofrequency energy to heat and destroy tumor tissue. The procedure is currently under clinical investigation and is not yet approved for this indication.

Who makes RF ablation?

RF ablation is developed by AngioDynamics, Inc., a company traded on the NASDAQ under the ticker ANGO. The company is conducting clinical research to evaluate the procedure's effectiveness in treating Non Small Cell Lung Cancer and pulmonary metastases.

What phase is RF ablation in?

RF ablation is in Phase 2 clinical development for Non Small Cell Lung Cancer and pulmonary metastases. It is an investigational procedure and has not yet received regulatory approval. One Phase 2 trial has been completed to evaluate its safety and efficacy.

What clinical trials is RF ablation in?

RF ablation was evaluated in a completed Phase 2 clinical trial with the identifier NCT00690703, titled 'Radiofrequency Ablation of Pulmonary Tumors Response Evaluation.' The trial enrolled 106 participants with Non Small Cell Lung Cancer and pulmonary metastases across the United States, Australia, Germany, Italy, and the United Kingdom.

Is RF ablation FDA approved?

RF ablation is not FDA approved for the treatment of Non Small Cell Lung Cancer or pulmonary metastases. It is an investigational procedure currently in clinical development. A Phase 2 trial has been completed, but the procedure remains under study and has not been cleared for this specific use.