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Enbrel liquid

Phase 3

Rheumatoid Arthritis | Small molecule | Immunology |Amgen Inc.|Last Updated: Jul 30, 2010

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment447

FDA Designations

No designations recorded

Clinical trial landscape

Enbrel liquid · 1 trial · 1 indication

Phase 3 1
NCT00249041Enbrel Liquid Immunogenicity ProtocolRheumatoid Arthritis
COMPLETED447 Analytics
PHASE3COMPLETED
Enbrel Liquid Immunogenicity Protocol
Rheumatoid ArthritisUnlock trial analytics

Study Endpoints

Primary Endpoints

Rates of anti-etanercept antibody formation to etanercept liquid with or without concomitant methotrexate (MTX) therapy at week 24
24 weeks

Secondary Endpoints

Rates of anti-etanercept antibody formation to etanercept liquid at week 12, and the rates of neutralizing antibodies at Weeks 12 and 24. Safety of etanercept liquid in RA subjects receiving 50 mg once weekly up to 24 weeks.
12 weeks and 24 weeks
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Etanercept liquidEXPERIMENTAL -

Interventions

NameTypeDescription
50 mg EtanerceptDRUG50 mg Etanercept liquid injected SC once weekly using prefilled syringes
Enbrel liquidDRUG50 mg Etanercept liquid injected SC once weekly using prefilled syringes
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo

Inclusion Criteria: * 18 years of age or older * Must be able to self-inject or have someone who can do so for them * Should have Rheumatoid Arthritis per ARA criteria and screening lab results per predefined value Exclusion Criteria: * Any prior biologic therapy for inflammatory disease * Any pr...

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Frequently asked questions about Enbrel liquid

What is Enbrel liquid used for in Rheumatoid Arthritis?

Enbrel liquid is used for Rheumatoid Arthritis. It is an investigational therapy being developed by Amgen Inc. for this condition. The drug is currently in Phase 3 clinical development, meaning it has not yet been approved and is still being studied for safety and efficacy in patients.

Who makes Enbrel liquid?

Enbrel liquid is being developed by Amgen Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol AMGN. Amgen is conducting clinical trials to evaluate the drug's safety and efficacy for the treatment of Rheumatoid Arthritis.

What phase is Enbrel liquid in?

Enbrel liquid is in Phase 3 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities. The Phase 3 trial for Enbrel liquid has been completed, with a total enrollment of 447 participants.

What clinical trials is Enbrel liquid in?

Enbrel liquid has one completed clinical trial, identified by the NCT number NCT00249041. This Phase 3 study, titled 'Enbrel Liquid Immunogenicity Protocol,' enrolled 447 participants with Rheumatoid Arthritis. The trial was uncontrolled and did not use randomization or double-blinding.

Is Enbrel liquid FDA approved?

Enbrel liquid is not FDA approved. It is an investigational drug currently in Phase 3 clinical development for Rheumatoid Arthritis. The completed Phase 3 trial, NCT00249041, has finished, but the drug has not yet received regulatory approval.