Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
GLYX-13/kg · 2 trials · 1 indication
| Arm | Type | Description |
|---|---|---|
| Placebo injection | PLACEBO_COMPARATOR | Normal saline |
| GLYX-13, 5 mg/kg | EXPERIMENTAL | Low dose of GLYX-13 |
| GLYX-13, 10 mg/kg | EXPERIMENTAL | High dose of GLYX-13 |
| Normal Saline | PLACEBO_COMPARATOR | IV placebo |
| GLYX-13, 1 mg/kg | EXPERIMENTAL | - |
| Name | Type | Description |
|---|---|---|
| GLYX-13 5 mg/kg | DRUG | Intravenous administration of 5 mg/kg into arm. |
| GLYX-13 10 mg/kg | DRUG | Intravenous administration of 10 mg/kg into arm. |
| Placebo | DRUG | Intravenous administration of normal saline into arm. |
| GLYX-13 | DRUG | single IV dose |
Inclusion Criteria: * Male and female subjects * Aged 18 to 65 years * Meets DSM-IV-TR) criteria for major depressive disorder (MDD) * Current episode has lasted ≥ 8 weeks before Screening with an inadequate response to all approved antidepressant agent(s) administered at an adequate dose and durat...
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