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APS

Phase 1

Osteoarthritis, Knee | Monoclonal antibody | Musculoskeletal |Zimmer Biomet Holdings, Inc.|Last Updated: Feb 14, 2019

Success Probability

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment11

FDA Designations

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Clinical trial landscape

APS · 1 trial · 1 indication

Phase 1 1
NCT02262364Safety of NStride Autologous Protein Solution in the Treatment of Knee Osteoarthritis (PROGRESS I)Osteoarthritis, Knee
COMPLETED11 Analytics
PHASE1COMPLETED
Safety of NStride Autologous Protein Solution in the Treatment of Knee Osteoarthritis (PROGRESS I)
Osteoarthritis, KneeUnlock trial analytics

Study Design & Arms

Interventions

NameTypeDescription
APSBIOLOGICALSee above
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Frequently asked questions about APS

What is APS used for in knee osteoarthritis?

APS is an investigational monoclonal antibody being developed for the treatment of knee osteoarthritis. It is intended to address the pain and functional limitations associated with this condition. The drug is currently in Phase 1 clinical development, meaning it is still being evaluated for safety and is not yet approved for commercial use.

What does APS target?

APS is a monoclonal antibody, which is a type of biologic drug designed to bind to a specific target in the body. However, the specific molecular target of APS has not been disclosed. The drug is being studied for its potential to treat knee osteoarthritis, a degenerative joint disease.

Who makes APS?

APS is being developed by Zimmer Biomet Holdings, Inc., a company traded on the New York Stock Exchange under the ticker symbol ZBH. Zimmer Biomet is a medical device company that also engages in biologic research and development, including the clinical evaluation of APS for knee osteoarthritis.

What phase is APS in?

APS is in Phase 1 clinical development. It has completed one Phase 1 trial, which was an uncontrolled study with 11 participants. The drug is still in the early stages of clinical testing, and it is not yet approved by regulatory authorities. Further studies would be needed to assess its safety and efficacy.

What clinical trials is APS in?

APS has been studied in one clinical trial, identified as NCT02262364, titled "Safety of NStride Autologous Protein Solution in the Treatment of Knee Osteoarthritis (PROGRESS I)." This Phase 1 trial was completed and enrolled 11 participants with knee osteoarthritis. The trial was not randomized or double-blinded and had no control group.