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Zalcitabine

Phase 2

HIV Infections | Small molecule | Infectious Disease |Roche Holding AG|Last Updated: Jun 24, 2005

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

Zalcitabine · 1 trial · 1 indication

Phase 2 1
NCT00002265An Open-Label, Multicenter Study to Evaluate the Safety and Tolerability of Dideoxycytidine (ddC) in Patients With AIDS or Advanced ARC Who Previously Demonstrated Intolerance to Zidovudine (AZT) in Protocol N3300 or N3492HIV Infections
COMPLETED- Analytics
PHASE2COMPLETED
An Open-Label, Multicenter Study to Evaluate the Safety and Tolerability of Dideoxycytidine (ddC) in Patients With AIDS or Advanced ARC Who Previously Demonstrated Intolerance to Zidovudine (AZT) in Protocol N3300 or N3492
HIV InfectionsUnlock trial analytics

Study Design & Arms

MaskingNONE
PurposeTREATMENT

Interventions

NameTypeDescription
ZalcitabineDRUG -
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Eligibility Criteria

Age Range13 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites9

Inclusion Criteria Concurrent Medication: Recommended: * Prophylactic aerosolized pentamidine. * Allowed for maintenance after recovering from infection for which initially prescribed: * Pyrimethamine. * Sulfadiazine. * Amphotericin. * Fluconazole. * Ketoconazole (= or \< 400 mg/day). * Acyclovir...

Countries:United States
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Frequently asked questions about Zalcitabine

What is Zalcitabine used for?

Zalcitabine is a small molecule drug being developed for the treatment of HIV infections. It is currently in Phase 2 clinical development and is being studied in patients with AIDS or advanced ARC who have shown intolerance to zidovudine (AZT).

Who makes Zalcitabine?

Zalcitabine is being developed by Roche Holding AG, which trades under the ticker RHHBY. The company is conducting clinical trials to evaluate the drug's safety and tolerability in patients with HIV infections.

What phase is Zalcitabine in?

Zalcitabine is in Phase 2 clinical development. It is an investigational drug and has not been approved by regulatory authorities. One Phase 2 trial has been completed, and there are no active trials currently ongoing.

What clinical trials is Zalcitabine in?

Zalcitabine has one completed clinical trial, identified as NCT00002265. This was an open-label, multicenter study conducted in the United States to evaluate the safety and tolerability of dideoxycytidine (ddC) in patients with AIDS or advanced ARC who previously demonstrated intolerance to zidovudine (AZT).

Is Zalcitabine the same as ddC?

Yes, Zalcitabine is also known as dideoxycytidine (ddC). In clinical trials, it is referred to by this alternative name, and the completed study NCT00002265 evaluates the safety and tolerability of ddC in patients with HIV infections.