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CP-778,875

Phase 2

Dyslipidemia | Small molecule | Metabolic |Pfizer, Inc.|Last Updated: May 7, 2009

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment84
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00326326Effect of CP-778,875 on HDL-C in Subjects With Abnormal Lipid Levels and Type 2 Diabetes.PHASE2 COMPLETED 84Jul 1, 2006Jun 1, 2007May 7, 200931 United States
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Study Endpoints
Primary Endpoints
HDL-C Safety and Efficacy
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Study Design & Arms
AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT
Interventions
NameTypeDescription
CP-778,875DRUG -
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Eligibility Criteria
Age Range30 Years — 70 Years
SexALL
Healthy VolunteersNo
Study Sites31

Inclusion Criteria: * HDL-C \< or = 45 mg/dL for men and \< or = 55 mg/dL for women * Triglycerides between 150-500 mg/dL * Fasting Plasma Glucose 140-240 mg/dL Exclusion Criteria: * Known cardiovascular, carotid, or peripheral vascular disease

Countries:United States
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