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APL 400-003

Phase 1

HIV Infections | Monoclonal antibody | Infectious Disease |Pfizer, Inc.|Last Updated: Jun 24, 2005

Success Probability

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Market & Valuation

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Trial Design

Double-BlindUNCONTROLLED
Total Trials2
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

APL 400-003 · 2 trials · 2 indications

Phase 1 2
NCT00002231Safety and Effects of Giving a New HIV Vaccine (GENEVAX-HIV) to HIV-Negative VolunteersHIV Infections
COMPLETED- Analytics
NCT00002232A Study of GENEVAX-HIV, a Possible VaccineHIV Infections
COMPLETED- Analytics
PHASE1COMPLETED
Safety and Effects of Giving a New HIV Vaccine (GENEVAX-HIV) to HIV-Negative Volunteers
HIV InfectionsUnlock trial analytics
PHASE1COMPLETED
A Study of GENEVAX-HIV, a Possible Vaccine
HIV InfectionsUnlock trial analytics

Study Design & Arms

MaskingNONE
PurposePREVENTION

Interventions

NameTypeDescription
APL 400-003BIOLOGICAL -
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Eligibility Criteria

Age Range18 Years to 60 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria You may be eligible for this study if you: * Are 18 - 60 years old. * Are HIV-negative and in good health. * Are able to understand how infections such as HIV are spread. * Agree to use effective methods of birth control during the study. Exclusion Criteria You will not be eli...

Countries:United States
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Frequently asked questions about APL 400-003

What is APL 400-003 used for?

APL 400-003 is an investigational monoclonal antibody being studied for HIV infections. It is in Phase 1 clinical development and has been evaluated in completed trials involving HIV-seronegative volunteers. The drug is not approved and remains under investigation for its potential use in HIV.

Who makes APL 400-003?

APL 400-003 is being developed by Pfizer, Inc., which trades under the ticker symbol PFE. The company is conducting clinical research on this investigational monoclonal antibody for HIV infections.

What phase is APL 400-003 in?

APL 400-003 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. Two Phase 1 trials have been completed, and the drug remains under study for HIV infections.

What clinical trials is APL 400-003 in?

APL 400-003 has been studied in two completed Phase 1 trials: NCT00002231 and NCT00002232. Both trials evaluated the safety and effects of the drug, also known as GENEVAX-HIV, in HIV-seronegative volunteers in the United States.

Is APL 400-003 the same as GENEVAX-HIV?

Yes, APL 400-003 is also known as GENEVAX-HIV. Clinical trials NCT00002231 and NCT00002232 refer to the drug by this alternative name, and both names describe the same investigational monoclonal antibody for HIV infections.