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Amniotic Allograft

Phase 3

Knee Osteoarthritis | Monoclonal antibody | Musculoskeletal |Organogenesis Holdings Inc.|Last Updated: Dec 22, 2025

Success Probability
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Market & Valuation
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Trial Design
UNCONTROLLED
Total Trials2
Total Enrollment1,110
FDA Designations
No designations recorded
Clinical trial landscape

Amniotic Allograft · 2 trials · 1 indication

Phase 3 2
NCT06000410A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the KneeKnee Osteoarthritis
COMPLETED594 Analytics
NCT04636229Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the KneeKnee Osteoarthritis
COMPLETED516 Analytics
PHASE3COMPLETED
A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee
Knee Osteoarthritis
NCT06000410594
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PHASE3COMPLETED
Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee
Knee Osteoarthritis
NCT04636229516
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Study Design & Arms
Interventions
NameTypeDescription
Amniotic Suspension AllograftBIOLOGICALThis investigational product is a cryopreserved product derived from human amnion and cells from the amniotic fluid.
PlaceboDRUGMatching placebo is 0.9% normal saline: 4 mL to be injected IA.
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Competitive Landscape -Osteoarthritis 114 trials (matched to "Knee Osteoarthritis")
CompanyTickerTrialsLead PhaseDrugs
Eli Lilly and CompanyLLY3PHASE3Eloralintide
Pacira Biosciences, Inc.PCRX4PHASE3ZILRETTA
Novo Nordisk A/S Sponsored ADR Class BNVO1PHASE3NNC0487-0111
Bioventus, Inc. Class ABVS1PHASE2PTP-001
Enlivex Ltd.ENLV2PHASE1Allocetra
Smith & Nephew plc Sponsored ADRSNN9 - Undisclosed
Stryker CorporationSYK11N/AUndisclosed
Zimmer Biomet Holdings, Inc.ZBH57N/AUndisclosed
Merit Medical Systems, Inc.MMSI1N/ACorticosteroid
Johnson & JohnsonJNJ1N/AUndisclosed
Abbott LaboratoriesABT1N/AUndisclosed
Enovis CorporationENOV1N/AUndisclosed
Teleflex IncorporatedTFX1 - Undisclosed
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