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MK1903

Phase 2

Dyslipidemia | Small molecule | Cardiovascular |Merck & Company, Inc.|Last Updated: Dec 21, 2015

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment191

FDA Designations

No designations recorded

Clinical trial landscape

MK1903 · 1 trial · 1 indication

Phase 2 1
NCT00847197A Study to Evaluate MK1903 in Patients With Dyslipidemia (MK1903-004)Dyslipidemia
COMPLETED191 Analytics
PHASE2COMPLETED
A Study to Evaluate MK1903 in Patients With Dyslipidemia (MK1903-004)
DyslipidemiaUnlock trial analytics

Study Endpoints

Primary Endpoints

Percent Change From Baseline in Low-Density Lipoprotein Cholesterol (LDL-C) (mg/dL)
Baseline and Week 4
Percent Change From Baseline in High-Density Lipoprotein Cholesterol (HDL-C) (mg/dL)
Baseline and Week 4

Secondary Endpoints

Percent Change From Baseline in Triglycerides (mg/dL)
Baseline and 4 Weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTALMK1903
2PLACEBO_COMPARATORPlacebo to MK1903

Interventions

NameTypeDescription
MK1903DRUGThree 50 mg capsules MK1903 by mouth every 8 hours for 4 weeks. All participants will receive placebo for a 2 week run-in period.
Comparator: PlaceboDRUGThree 50 mg capsules placebo to MK1903 every 8 hours for 4 weeks. All participants will receive placebo for a 2 week run-in period.
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Eligibility Criteria

Age Range18 Years to 70 Years
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Participant is not on a statin or other lipid-modifying therapy * Low or moderate risk participant * Male participants, and female participants not of reproductive potential Exclusion Criteria: * Female participant of reproductive potential * Participant is pregnant, breastf...

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Frequently asked questions about MK1903

What is MK1903 used for?

MK1903 is an investigational small molecule being developed for the treatment of dyslipidemia, a condition characterized by abnormal levels of lipids in the blood. It is being studied in patients with dyslipidemia as part of a clinical development program.

Who makes MK1903?

MK1903 is being developed by Merck & Company, Inc., a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol MRK. The company is conducting clinical trials to evaluate the drug's safety and efficacy in patients with dyslipidemia.

What phase is MK1903 in?

MK1903 is in Phase 2 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities and is still being studied in clinical trials to assess its safety and effectiveness for treating dyslipidemia.

What clinical trials is MK1903 in?

MK1903 has been studied in a Phase 2 clinical trial with the identifier NCT00847197, titled "A Study to Evaluate MK1903 in Patients With Dyslipidemia (MK1903-004)." This trial enrolled 191 participants and has been completed.

Is MK1903 the same as any other drug?

MK1903 is a distinct investigational compound developed by Merck & Company, Inc. No alternative names for MK1903 have been reported in the context of its clinical development for dyslipidemia.