Recent Updates
Recently added Catalysts

MK0686

Phase 2

Osteoarthritis | Small molecule | Musculoskeletal |Merck & Company, Inc.|Last Updated: Jun 26, 2015

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment150

FDA Designations

No designations recorded

Clinical trial landscape

MK0686 · 2 trials · 2 indications

Phase 2 2
NCT00296569A Study to Assess the Safety and Efficacy of an Investigational Drug (MK-686) in Patients With Osteoarthritis (0686-006)Osteoarthritis
COMPLETED150 Analytics
NCT00533403MK0686 in Postsurgery Dental Pain (0686-002)Pain, Postoperative
COMPLETED114 Analytics
PHASE2COMPLETED
A Study to Assess the Safety and Efficacy of an Investigational Drug (MK-686) in Patients With Osteoarthritis (0686-006)
OsteoarthritisUnlock trial analytics
PHASE2COMPLETED
MK0686 in Postsurgery Dental Pain (0686-002)
Pain, PostoperativeUnlock trial analytics

Study Endpoints

Primary Endpoints

Pain relief at the knee and hip over 4 weeks of treatment as assessed by the WOMAC Pain Subscale.
over 4 weeks of treatment

Secondary Endpoints

Safety and tolerability over a 4-week treatment period
over a 4-week treatment period
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
MK0686DRUG -
Unlock Study Design Details

Eligibility Criteria

Age Range40 Years to 65 Years
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Patients with a clinical and radiographic diagnosis of osteoarthritis of the hip or knee,either prior NSAID or Acetaminophen users within the ARA functional class I,II or III and with no clinically significant diseases * Patients required to demonstrate a flare of the signs an...

Unlock Eligibility Criteria

Frequently asked questions about MK0686

What is MK0686 used for?

MK0686 is an investigational small molecule being studied for the treatment of pain, including postoperative pain and osteoarthritis. It is currently in Phase 2 clinical development and is not yet approved by regulatory authorities.

Who makes MK0686?

MK0686 is being developed by Merck & Company, Inc., which is publicly traded under the ticker symbol MRK. The company is conducting clinical trials to evaluate the safety and efficacy of this investigational drug.

What phase is MK0686 in?

MK0686 is in Phase 2 clinical development. Clinical trials for this investigational drug have been completed, and it remains under study for pain-related conditions. It is not approved for commercial use.

What clinical trials is MK0686 in?

MK0686 has been studied in two completed Phase 2 clinical trials. One trial, NCT00296569, enrolled 150 patients with osteoarthritis. Another trial, NCT00533403, enrolled 114 patients with postsurgery dental pain.

Is MK0686 the same as MK-686?

Yes, MK0686 is also referred to as MK-686. Clinical trial records use both names to describe the same investigational drug being developed by Merck & Company, Inc. for pain and osteoarthritis.