Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Indinavir · 7 trials · 1 indication
| Name | Type | Description |
|---|---|---|
| Indinavir sulfate | DRUG | - |
| Lamivudine | DRUG | - |
| Stavudine | DRUG | - |
| Zidovudine | DRUG | - |
| Efavirenz | DRUG | - |
| Levocarnitine | DRUG | - |
| Adefovir dipivoxil | DRUG | - |
| Nelfinavir mesylate | DRUG | - |
| Ritonavir | DRUG | - |
Inclusion Criteria Patients must have: * HIV-1 seropositive status. * CD4 count greater than 100 cells/mm3. * Viral RNA above 10,000 copies/mL. * Consent from parent or guardian if less than 18 years of age. Exclusion Criteria Prior Medication: Excluded: * Prior therapy with protease inhibitor...
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Indinavir is used for the treatment of HIV infections. It is a small molecule drug being developed by Merck & Company, Inc. (MRK) and is currently in Phase 3 clinical development for this indication.
Indinavir is a protease inhibitor used in HIV therapy. It works by inhibiting the HIV protease enzyme, which is essential for the virus to mature and become infectious. This mechanism helps reduce viral load in HIV-positive patients.
Indinavir is developed by Merck & Company, Inc., a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol MRK. The drug is currently in Phase 3 clinical trials for HIV infections.
Indinavir is in Phase 3 clinical development for the treatment of HIV infections. It is an investigational drug and has not yet been approved by regulatory authorities. The development program includes completed trials across Phase 1, Phase 2, and Phase 3.
Indinavir has been studied in seven clinical trials, all of which are completed. Key trials include NCT00002235 (Phase 2, n=6), NCT00002351 (Phase 1, n=12), NCT00002361 (Phase 2, n=30), and NCT00002406 (Phase 3, n=350). All trials were conducted in the United States.
Indinavir is also known by the brand name Crixivan. This alternative name is used to refer to the same drug, which is being developed by Merck & Company, Inc. for the treatment of HIV infections.