Recent Updates
Recently added Catalysts

DRM02

Phase 2

Psoriasis | Small molecule | Dermatology |Eli Lilly and Company|Last Updated: Jul 20, 2021

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDBiomarker
Total Trials1
Total Enrollment23

FDA Designations

No designations recorded

Clinical trial landscape

DRM02 · 2 trials · 2 indications

Phase 2 2
NCT01993433A Safety and Efficacy Study of DRM02 in Subjects With Plaque PsoriasisPsoriasis
COMPLETED23 Analytics
NCT01993446A Safety and Efficacy Study of DRM02 in Subjects With RosaceaRosacea
COMPLETED30 Analytics
PHASE2COMPLETED
A Safety and Efficacy Study of DRM02 in Subjects With Plaque Psoriasis
PsoriasisUnlock trial analytics
PHASE2COMPLETED
A Safety and Efficacy Study of DRM02 in Subjects With Rosacea
RosaceaUnlock trial analytics

Study Endpoints

Primary Endpoints

Change in Physician's Lesion Assessment
Week 6
Change in inflammatory lesion count
Week 6

Secondary Endpoints

Physician's Lesion Assessment
From baseline to weeks 0, 1, 2, 3, 4 and 6
PLA dichotomized into "success" and "failure"
Week 6
Investigator's Global Evaluation (IGE)
From baseline to weeks 0, 1, 2, 3, 4 and 6
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
DRM02EXPERIMENTALDRM02 Topical Gel, 0.25%
VehiclePLACEBO_COMPARATORDRM02 Topical Gel, Vehicle

Interventions

NameTypeDescription
DRM02DRUG -
VehicleOTHER -
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to 70 Years
SexALL
Healthy VolunteersNo
Study Sites2

Inclusion Criteria: * Male or female 18 to 70 years of age. * Plaque-type psoriasis with two lesions of similar size and have an identical score of at least 6 but no more than 8 on the sum of the individual components of the Severity of Psoriasis Area Severity Index (PASI) at the Target Lesion scal...

Countries:Canada
Unlock Eligibility Criteria

Frequently asked questions about DRM02

What is DRM02 used for?

DRM02 is an investigational small molecule being studied for the treatment of plaque psoriasis and rosacea. It is in Phase 2 clinical development for these dermatological conditions. The drug is being developed by Eli Lilly and Company.

Who makes DRM02?

DRM02 is being developed by Eli Lilly and Company, a pharmaceutical company traded on the New York Stock Exchange under the ticker LLY. The drug is currently in Phase 2 clinical trials for psoriasis and rosacea.

What phase is DRM02 in?

DRM02 is in Phase 2 clinical development. It has completed two Phase 2 trials, one in plaque psoriasis and one in rosacea. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is DRM02 in?

DRM02 has completed two Phase 2 clinical trials. NCT01993433 studied the drug in subjects with plaque psoriasis, and NCT01993446 studied it in subjects with rosacea. Both trials were completed in Canada and enrolled adults aged 18 years and older.

Is DRM02 the same as any other drug?

DRM02 is the name used in clinical trials for this investigational small molecule. No alternative names have been reported for this drug in the available clinical trial information.