Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT03370887 | AZD8601 Study in CABG Patients | PHASE2 | COMPLETED | 11 | — | — | Feb 5, 2018 | Jun 30, 2021 | Oct 10, 2024 | 10 | United States, Finland +3 |
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
Values are classified as high if they are above the normal reference range, based on local lab reference ranges.
| Arm | Type | Description |
|---|---|---|
| Low dose AZD8601 (3 mg) | EXPERIMENTAL | 8 patients will be randomised to receive 3 mg AZD8601 |
| High dose AZD8601 (30 mg) | EXPERIMENTAL | 8 patients will be randomised to receive 30 mg AZD8601 |
| Placebo | PLACEBO_COMPARATOR | 8 patients will be randomised to receive placebo injections |
| Name | Type | Description |
|---|---|---|
| AZD8601 | DRUG | AZD8601 solution for injection, 0,5 mg/mL and 5 mg/mL will be given as 30 injections of 0.1 mg (3 mg per patient), or 1 mg (30 mg per patient) respectively on a single occasion |
| Placebo | DRUG | Placebo for AZ8601 injection for solution will be given as 30 injections per patient on a single occasion |
Inclusion Criteria: For inclusion in the study patients should fulfil the following criteria at Visit 1 and/or 2: 1\. Provision of signed and dated informed consent prior to any study specific procedures Males and females: 1. Males must be surgically sterile or using an acceptable method of cont...