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Illumina, Inc.

ILMNFDA catalysts, PDUFA dates & pipeline intelligence
$270.07
▲ +0.68 · +0.25%

Financials

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R&D Expenses
Operating CF
Total Assets
Total Liabilities
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Quarterly Cash
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52W LOW $94.0052W HIGH $309.35
Volume
536.02 K
Value Traded
322.84 M
Short % Float
6.29%
Days to Cover
1.6
+2.79%Week
-0.7%1 Month
+42.5%3 Month
+110.08%6 Month
-62.64%5 Year
+894.78%All Time

Cash Data

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  • Monthly Burn
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Key Stats

Market Cap
40.78 B
EPS (TTM)
5.46
P/E Ratio
49.42
Ent. Value
39.52 B
Total Shares
151.00 M
Float Shares
150.48 M
Insiders
0.34%
Institutions
114.54%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

ILMN Catalyst Timeline

Dated clinical, regulatory and corporate events for Illumina, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Illumina, Inc.

346Total events
8Upcoming
79Tier-1 (high impact)
2020 to 2027Coverage

Upcoming catalysts 2

T2Quarterly Update
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T2R&D Day
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Event history 50

●R&D DayPresentation
Illumina Industry Education session at ASHG booth
▲Product LaunchPost-Market
Early access availability of DRAGEN Ultra, BioInsight Platform Workflow Orchestrator, and Learning Cohorts
▲Product LaunchSpliceAI2Post-Market
Newly announced SpliceAI2 model for rare disease research
rare diseasesource ↗
▲Product LaunchPost-Market
Newly released DRAGEN v4.6 expands deployment options across cloud and CPU environments
▲Product LaunchPost-Market
Illumina launches BioInsight Platform, its first unified software environment
▲Platform ValidationSpliceAI2Preclinical
SpliceAI2 identified 17% more disease-relevant splice variants than other models in rare disease research dataset
rare disease researchsource ↗
▲PreprintSpliceAI2Presentation
Preprint released evaluating SpliceAI2 performance vs original SpliceAI and alternative splice prediction models
▲Product LaunchPost-Market
Illumina BioInsight Platform debuted
▲Quarterly UpdateCorporate
Illumina reports Q2 2026 financial results
▲Runway Guidance UpdateCorporate
Illumina raises FY2026 revenue and EPS guidance
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How ILMN actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
-Example Drug Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
1
Drugs Scored
rNPV / MCap
Top Drug
Top 67%
Mid Cap
(rank 441 of 657)
Percentile Rank
Showing 1 of 1 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
18F-mFBG for administration Small moleculeNCT04535193Cardiovascular DiseasesPhase 1 ACTIVE NOT_RECRUITING 10Aug 30, 2026
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every ILMN program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
advanced cancer2023-05-30improved survival in cancer patients who received CGP testing and targeted therapy compared to standard chemotherapyRead MoreReal-world study data reveals better outcomes for cancer patients who receive comprehensive genomic testing Illumina Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, today announced some of the latest data on the impact...Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Meister Keith A.DirectorSell -7,500 882,351 held$217.28 09/04/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Casdin Capital, LLC 4.7 % (-4.1 %) 93.19 M 530.00 K
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

ILMN Institutional Ownership Trends

ILMN Short Interest

Shares sold short, counted twice a month.

6.29%
Short % of Float
of tradable shares sold short
9.5M
Shares Sold Short
-10.5% vs prior count
1.6 Low
Days to Cover
trading days of normal volume to buy every short share back
5.8M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-20
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Live calls and puts by strike: last price, volume and open interest for every expiry.
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How ILMN ranks across every disease it competes in

Competitive Position is a premium feature
See how ILMN ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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ILMN News

ILMN
Oct 21, 2026
ILMNGeneral
▲ +5.6%on this news

Illumina BioInsight Platform expands with new software to accelerate the path from sequencing to discovery

Illumina has launched three early-access capabilities on its BioInsight Platform, including DRAGEN Ultra, Workflow Orchestrator, and Learning Cohorts. These tools aim to accelerate the transition from sequencing data to discovery by automating workflows and enhancing data analysis. The innovations support diverse research applications, including rare diseases and population genomics.

Read more →
ILMN
Oct 20, 2026
ILMNConferences/Events
▲ +5.6%on this newsshared move

Illumina To Webcast Upcoming Investor Conference

Illumina, Inc. announced its participation in the UBS Global Healthcare Conference on November 10, 2026. The management team will engage in a fireside chat scheduled for 07:15am PT. Investors can access the webcast through Illumina's website, with a replay available for 30 days.

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ILMN
Oct 14, 2026
ILMNGeneral

Illumina launches BioInsight Platform, its first unified software environment to help accelerate genomic and multiomic breakthroughs

Illumina has launched the BioInsight Platform, a unified software environment aimed at transforming complex genomic and multiomic data into actionable insights. The platform integrates advanced analysis tools, AI innovations, and curated biological data, allowing researchers to streamline their workflows. Additionally, the latest DRAGEN update enhances accessibility for secondary analysis across various computing environments.

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ILMN
Oct 8, 2026
ILMNConferences/Events
▲ +5.1%on this newsshared move

Illumina to Announce Third Quarter 2026 Financial Results on Thursday, October 29, 2026

Illumina, Inc. has announced that it will release its third quarter 2026 financial results on October 29, 2026. Following the results, CEO Jacob Thaysen and CFO Ankur Dhingra will host a conference call to discuss the outcomes with analysts and investors. The call will be accessible via Illumina's website, with a replay available for 30 days post-event.

Read more →
ILMN
Oct 8, 2026
ILMNGeneral

Illumina releases SpliceAI2 to help advance rare disease research

Illumina has launched SpliceAI2, a genomic AI model that enhances the identification of disease-relevant splice variants. Compared to previous models, SpliceAI2 identified 17% more relevant variants in rare disease research datasets. This advancement is part of Illumina's broader effort to improve genomic data interpretation and support researchers in understanding genetic variations. The model is now accessible through Illumina's BioInsight applications.

Read more →
ILMN
Jul 30, 2026
ILMNGeneral

Illumina Reports Financial Results for Second Quarter of Fiscal Year 2026

Illumina, Inc. reported a revenue of $1.16 billion for Q2 2026, marking a 9.5% increase from Q2 2025. The company also raised its fiscal year guidance, anticipating total revenue between $4.60 billion and $4.64 billion. CEO Jacob Thaysen highlighted strong demand for their NovaSeq X technology, although operating margins showed a slight decline compared to the previous year.

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ILMN
Jul 16, 2026
ILMNGeneral

Illumina expands Billion Cell Atlas program with new AI drug developers

Illumina has expanded its Billion Cell Atlas program by adding three new AI-driven drug developers, including Formation Bio. This collaboration aims to utilize Illumina's extensive genomic data to enhance drug discovery and development. The initiative is expected to help in identifying effective treatments and improving clinical trial designs, ultimately benefiting patient outcomes.

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ILMN
Jul 16, 2026
ILMNGeneral

Juno Bio Opens First CLIA-Certified Sequencing Lab Dedicated Entirely to Women's Health, Backed by Ada Ventures, Artesian, Illumina Accelerator, and Entrepreneur First

Juno Bio has launched its first CLIA-certified sequencing lab focused on women's health, enhancing precision vaginal microbiome testing. The company secured $3.8 million in funding from notable investors to support this initiative. The lab aims to provide clinically actionable insights into vaginal health, addressing common but often misunderstood conditions. This development is expected to significantly improve care for women facing recurrent health issues.

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ILMN
Jul 14, 2026
ILMNGeneral

Element Biosciences Prevails in German Patent Case Against Illumina

Element Biosciences has secured a favorable ruling from the Regional Court of Munich I, determining that Illumina infringed on its patent rights related to an imaging method for DNA sequencing. The court found both direct and indirect infringement by Illumina, which may impact their operations in Germany. This ruling strengthens Element's position in the competitive biopharma landscape.

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ILMN
Jul 14, 2026
ILMNPhases

Illuminare Biotechnologies Appoints Veteran Biopharmaceutical Leader as New CEO

Illuminare Biotechnologies has appointed Brian Longstreet as CEO, effective June 1, 2026. His extensive experience in the biopharmaceutical sector is expected to guide the company through its Phase 2/3 development and commercialization. The company is set to initiate a Phase 2 trial for its product, Illuminare-1, following positive Phase 1 results.

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ILMN
Jul 9, 2026
ILMNConferences/Events

Illumina to Announce Second Quarter 2026 Financial Results on Thursday, July 30, 2026

Illumina, Inc. will release its second quarter 2026 financial results on July 30, 2026. Following the announcement, CEO Jacob Thaysen and CFO Ankur Dhingra will host a conference call to discuss the results. Interested parties can access the call via Illumina's website, with a replay available for 30 days post-event.

Read more →
ILMN
Jul 9, 2026
ILMNGeneral

Illumina appoints Michael Sullivan Chief Commercial Officer and Julie Coletti Chief Legal Officer

Illumina has appointed Mike Sullivan as Chief Commercial Officer and Julie Coletti as Chief Legal Officer, effective July 20 and August 3, 2026, respectively. These appointments are aimed at strengthening the company's leadership as it continues to advance its strategy in genomics and human health. Sullivan brings extensive experience in commercial leadership, while Coletti has a strong background in legal and regulatory affairs.

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ILMN
Jul 8, 2026
ILMNGeneral

Bifrost Biosystems Pens Agreement with Illumina for Supply of Sequencing Chemistry for Optical Pooled Screening Platform

Bifrost Biosystems has entered into a commercial supply agreement with Illumina to incorporate Illumina's sequencing-by-synthesis chemistry into its optical pooled screening platform. This collaboration aims to enhance the platform's capabilities, which will be available for commercial use in early 2027. The agreement ensures reliable access to essential sequencing technology for Bifrost.

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ILMN
Jun 23, 2026
ILMNGeneral

Daniel M. Skovronsky, MD, PhD, appointed to Illumina's Board of Directors

Illumina, Inc. has appointed Daniel M. Skovronsky, MD, PhD, to its Board of Directors, effective June 16, 2026. Skovronsky, currently the Chief Scientific and Product Officer at Eli Lilly, brings significant experience in drug discovery and clinical development. His expertise is anticipated to bolster Illumina's capabilities in genomics and precision medicine.

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ILMN
Jun 8, 2026
ILMNGeneral

Illumina launches StrataMap Spatial Solution, a powerful end-to-end spatial whole transcriptome research solution

Illumina launched the StrataMap Spatial Solution, a new end-to-end sequencing-based tool for spatial transcriptomics research. The technology provides single-cell resolution across a large capture area to map tissue structure and function. It detects twice as many unique genes per sample compared to probe-based alternatives. The system processes over 2000 samples annually and delivers results in under five days.

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ILMN
Jun 2, 2026
ILMNGeneral

Integrated DNA Technologies Announces End-to-End Oncology Research Workflows Optimized on Illumina Software for Faster Insights

Integrated DNA Technologies (IDT) has announced a collaboration with Illumina to enhance oncology research workflows. This partnership integrates IDT's library preparation with Illumina's DRAGEN secondary analysis platform, aiming to streamline the process from sequencing to insights. The collaboration focuses on improving analysis for FFPE and cfDNA samples, ultimately supporting advancements in cancer research.

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ILMN
May 28, 2026
ILMNGeneral
▲ +5.7%on this newsshared move

Illumina introduces the first distributed whole-genome sequencing solution for highly sensitive MRD research

Illumina, Inc. has announced the launch of a new whole-genome sequencing solution aimed at molecular residual disease (MRD) research. This distributed kit will allow laboratories to more effectively adopt MRD detection protocols for clinical research. Currently in early access for select partners, the solution offers high analytical sensitivity and quick turnaround times, making it suitable for detecting early-stage tumors. Early evaluations, including studies at the Mayo Clinic, indicate strong concordance with previous clinical results, suggesting promising potential for wider clinical application.

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ILMN
May 28, 2026
ILMNGeneral
▲ +5.7%on this newsshared move

Illumina and SPT Labtech unveil fireflyGO, enabling faster, simpler targeted oncology research

Illumina and SPT Labtech have launched the fireflyGO automation platform, designed to streamline targeted oncology research. This new solution integrates with the MiSeq i100 Series, enhancing workflow efficiency and accessibility in genomic testing. The platform aims to reduce manual processes and improve turnaround times for cancer testing, while expanding Illumina's oncology research portfolio.

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ILMN
May 21, 2026
ILMNGeneral

David P. King elected to Illumina's Board of Directors

Illumina, Inc. has announced the election of David P. King to its Board of Directors, effective immediately. King, the former Chairman and CEO of Labcorp, brings significant expertise in healthcare and diagnostics, which aligns with Illumina's goal of integrating genomics more deeply into standard healthcare practices. His leadership experience and knowledge in the industry is expected to bolster Illumina's clinical strategy and long-term impact on patients and shareholders. This change follows the retirement of three directors from the Board.

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ILMN
May 19, 2026
ILMNGeneral

Illumina releases 2025 Corporate Responsibility Report, expanding access to genomics and accelerating global impact

Illumina Inc. has released its 2025 Corporate Responsibility Report, showcasing its efforts to enhance access to genomics and its sustainability initiatives. The report highlights partnerships aimed at population-scale genomics and the company's achievements in reducing environmental impact. Illumina's commitment to community engagement and innovation in genomic technologies is also emphasized.

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About Illumina, Inc.

San Diego, CA 8,650 employees illumina.com
Headquarters5200 ILLUMINA WAY, SAN DIEGO, CA, 92122
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