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AZD5438

Phase 1

Neoplasms | Small molecule | Oncology |AstraZeneca PLC|Last Updated: Jan 26, 2011

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment -
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00088790AZD5438 in Patients With Advanced Solid MalignanciesPHASE1 COMPLETED -Jul 1, 2004Dec 1, 2005Jan 26, 20112 United States
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Study Design & Arms
PurposeTREATMENT
Interventions
NameTypeDescription
AZD5438DRUG -
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites2

Inclusion Criteria: * Advanced solid malignancy * Cancer refractory to standard treatments or for which no standard therapy exits Exclusion Criteria: * Radiotherapy within 3 weeks of the start of treatment * Investigational product within the last 3 weeks * Systemic cytotoxic anti-cancer therapy ...

Countries:United States
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