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Apitox, purified honeybee toxin, lyophilized in saline

Phase 3

Osteoarthritis of the Knee | Monoclonal antibody | Musculoskeletal |Apimeds Pharmaceuticals US, Inc.|Last Updated: Dec 13, 2016

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment363

FDA Designations

No designations recorded

Clinical trial landscape

Apitox, purified honeybee toxin, lyophilized in saline · 1 trial · 1 indication

Phase 3 1
NCT01112722Apitox, Honeybee Toxin for Pain and Inflammation of OsteoarthritisOsteoarthritis of the Knee
COMPLETED363 Analytics
PHASE3COMPLETED
Apitox, Honeybee Toxin for Pain and Inflammation of Osteoarthritis
Osteoarthritis of the KneeUnlock trial analytics

Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
PurposeTREATMENT

Interventions

NameTypeDescription
Apitox, purified honeybee toxin, lyophilized in salineBIOLOGICALintradermal injections of 0.1mg apitox in 0.1ml WFI over 12 weeks treatment period, injections twice weekly range from 1 to 20 injections
histamineBIOLOGICALimitates pain and erythema of honeybee venom
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Competitive Landscape -Osteoarthritis 115 trials (matched to "Osteoarthritis of the Knee")

Frequently asked questions about Apitox, purified honeybee toxin, lyophilized in saline

What is Apitox used for?

Apitox is being developed for the treatment of osteoarthritis of the knee. It is a purified honeybee toxin formulation that is lyophilized in saline. The drug is intended to address pain and inflammation associated with knee osteoarthritis, a musculoskeletal condition.

Who is developing Apitox?

Apitox is being developed by Apimeds Pharmaceuticals US, Inc., which trades under the ticker symbol APUS. The company is responsible for the clinical development of this purified honeybee toxin product.

What phase is Apitox in?

Apitox is in Phase 3 clinical development. The program includes one completed Phase 3 trial, and there are currently no active trials listed. The drug remains investigational and has not been approved by the FDA.

What clinical trials is Apitox in?

Apitox has been studied in a single Phase 3 clinical trial, NCT01112722, titled "Apitox, Honeybee Toxin for Pain and Inflammation of Osteoarthritis." The trial was completed, enrolled 363 participants, and was conducted in the United States.

Is Apitox the same as purified honeybee toxin?

Yes, Apitox is also known as purified honeybee toxin, lyophilized in saline. These terms refer to the same investigational product being developed by Apimeds Pharmaceuticals US, Inc. for knee osteoarthritis.