Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT01444365 | A Study of ABT-652 in Combination With a Nonsteroidal Anti-Inflammatory Drug (NSAID) in Adults With Osteoarthritis Pain of the Knee | PHASE2 | COMPLETED | 202 | — | — | Oct 1, 2011 | Apr 1, 2012 | May 15, 2013 | 31 | United States |
Subject reported 24-hour average pain score measured by Visual Analogue Scale
| Arm | Type | Description |
|---|---|---|
| ABT-652 NSAID | EXPERIMENTAL | ABT-652 capsules -2 ABT-652 capsules twice daily (add-on) NSAID - as prescribed |
| Placebo NSAID | PLACEBO_COMPARATOR | Placebo - 2 placebo capsules twice daily NSAID - as prescribed |
| Name | Type | Description |
|---|---|---|
| ABT-652 NSAID | DRUG | ABT-652 capsules - 2 ABT-652 capsules twice daily (add-on) NSAID- as prescribed |
| Placebo NSAID | DRUG | Placebo - 2 placebo capsules twice daily NSAID- as prescribed |
Inclusion Criteria: * History of osteoarthritis (OA) of the knee joint and meeting American College of Rheumatology (ACR) Clinical and Radiographic criteria, * Currently taking nonsteroidal anti-inflammatory drugs (NSAIDs) and still experiencing pain as per the protocol requirements. * Willing to w...