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BD MDI 320 µg

Phase 2

Asthma | Small molecule | Respiratory |cbdMD, Inc.|Last Updated: Jun 6, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDBiomarker
Total Trials1
Total Enrollment147

FDA Designations

No designations recorded

Clinical trial landscape

BD MDI 320 µg · 1 trial · 1 indication

Phase 2 1
NCT02105012Study to Assess the Efficacy and Safety of Budesonide (PT008) in Adult Subjects With Mild to Moderate Persistent AsthmaAsthma
COMPLETED147 Analytics
PHASE2COMPLETED
Study to Assess the Efficacy and Safety of Budesonide (PT008) in Adult Subjects With Mild to Moderate Persistent Asthma
AsthmaUnlock trial analytics

Study Endpoints

Primary Endpoints

Change From Baseline in Morning Pre-dose Trough Forced Expiratory Volume in 1 Second (FEV1) at the End of the Treatment Period
Baseline to End of Treatment Period (Day 29 or Day 15 if Day 29 is missing)

Change from baseline in morning pre-dose trough Forced Expiratory Volume in 1 second (FEV1) at the end of the Treatment Period.

Secondary Endpoints

Change From Baseline in Mean Morning Pre-dose Diary Peak Expiratory Flow Rate (PEFR)
Baseline to Last 7 Days of Treatment Period
Change From Baseline in Mean Evening Pre-dose Diary Peak Expiratory Flow Rate (PEFR)
Baseline to Last 7 Days of Treatment Period
Change From Baseline in Mean Number of Puffs of Rescue Ventolin HFA
Baseline to Last 7 Days of Treatment
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
BD MDI 320 µgEXPERIMENTALBudesonide metered dose inhaler (BD MDI) 320 µg (PT008) administered as 2 inhalations BID
BD MDI 160 µgEXPERIMENTALBD MDI 160 µg (PT008) administered as 2 inhalations BID
BD MDI 80 µgEXPERIMENTALBD MDI 80 µg (PT008) administered as 2 inhalations BID
BD MDI 40 µgEXPERIMENTALBD MDI 40 µg (PT008) administered as 2 inhalations BID
Placebo MDIPLACEBO_COMPARATORPlacebo MDI administered as 2 inhalations BID

Interventions

NameTypeDescription
BD MDI 320 µgDRUGBudesonide Inhalation Aerosol administered as 2 inhalations BID
BD MDI 160 µgDRUGBudesonide Inhalation Aerosol administered as 2 inhalations BID
BD MDI 80 µgDRUGBudesonide Inhalation Aerosol administered as 2 inhalations BID
BD MDI 40 µgDRUGBudesonide Inhalation Aerosol administered as 2 inhalations BID
Placebo MDIDRUGPlacebo MDI administered as 2 inhalations BID
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites41

Inclusion Criteria: * ≥ 18 - 65 years of age * Diagnosis of mild to moderate persistent asthma, diagnosed at least 6 months prior to screening * Currently receiving treatment with a low to medium dose of an inhaled corticosteroid (ICS) OR a combination of controller medications for at least 4 weeks...

Countries:United States
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Frequently asked questions about BD MDI 320 µg

What is BD MDI 320 µg used for?

BD MDI 320 µg is an investigational small molecule being developed for the treatment of asthma. It is a metered-dose inhaler formulation of budesonide, a corticosteroid, intended for use in adult patients with mild to moderate persistent asthma. The drug is currently in clinical development and has not been approved by regulatory authorities.

Who makes BD MDI 320 µg?

BD MDI 320 µg is being developed by cbdMD, Inc., a company publicly traded under the ticker symbol YCBD on the stock market. The company is conducting clinical research to evaluate the safety and efficacy of this investigational asthma treatment.

What phase is BD MDI 320 µg in?

BD MDI 320 µg is in Phase 2 clinical development. It has completed one Phase 2 trial, which was a randomized, double-blind, placebo-controlled study. The drug remains investigational and has not received FDA approval for any use.

What clinical trials is BD MDI 320 µg in?

BD MDI 320 µg has been studied in one completed Phase 2 clinical trial with the identifier NCT02105012. This trial, titled 'Study to Assess the Efficacy and Safety of Budesonide (PT008) in Adult Subjects With Mild to Moderate Persistent Asthma,' enrolled 147 participants in the United States.

Is BD MDI 320 µg the same as budesonide?

BD MDI 320 µg is a formulation of budesonide, a corticosteroid medication. The clinical trial for BD MDI 320 µg was conducted under the name PT008, which is another designation for the same investigational drug. It is delivered via a metered-dose inhaler for the treatment of asthma.