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ciclesonide

Phase 3

Asthma | Small molecule | Respiratory |Takeda Pharmaceutical Company Limited|Last Updated: Oct 21, 2009

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindACTIVE_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment26

FDA Designations

No designations recorded

Clinical trial landscape

ciclesonide · 1 trial · 1 indication

Phase 3 1
NCT00525772Effect of Ciclesonide on Exercise Induced BronchoconstrictionAsthma
COMPLETED26 Analytics
PHASE3COMPLETED
Effect of Ciclesonide on Exercise Induced Bronchoconstriction
AsthmaUnlock trial analytics

Study Endpoints

Primary Endpoints

change in maximum fall in FEV1 induced by dry air exercise challenge after treatment compared to the respective pretreatment value
at 1 week of treatment

Secondary Endpoints

Changes in sputum cell counts,bronchial responsiveness to mannitol and other clinical parameters of asthma control after treatment compared to respective pre-treatment value.
after 1, 2, 3, weeks of treatment
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1ACTIVE_COMPARATORciclesonide 50 and 200ug
2ACTIVE_COMPARATORciclesonide 100ug and 400ug

Interventions

NameTypeDescription
ciclesonideDRUGlow dose- 50ug and 200ug
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Eligibility Criteria

Age Range12 Years to 30 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * stable asthma not on maintenance asthma medications * exercise induced bronchoconstriction on dry air exercise challenge. Exclusion Criteria: * other significant co-morbidity or treatments that might interfere with the conduct or results of the study * fail to return to base...

Countries:Canada
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Frequently asked questions about ciclesonide

What is ciclesonide used for?

Ciclesonide is used for asthma. It is a small molecule being developed by Takeda Pharmaceutical Company Limited for the treatment of asthma, a respiratory condition. The drug is currently in Phase 3 clinical development for this indication.

What does ciclesonide target?

Ciclesonide is a small molecule developed for asthma. The specific molecular target of ciclesonide is not disclosed in the available information. It is being studied for its effects on exercise-induced bronchoconstriction in patients with asthma.

Who makes ciclesonide?

Ciclesonide is being developed by Takeda Pharmaceutical Company Limited, a company listed on the stock exchange under the ticker TAK. Takeda is conducting clinical trials to evaluate the drug for the treatment of asthma.

What phase is ciclesonide in?

Ciclesonide is in Phase 3 clinical development for asthma. It is an investigational drug, meaning it has not yet been approved by regulatory authorities. The drug is being studied in a completed Phase 3 trial to assess its efficacy and safety.

What clinical trials is ciclesonide in?

Ciclesonide has one completed Phase 3 clinical trial with the identifier NCT00525772, titled 'Effect of Ciclesonide on Exercise Induced Bronchoconstriction'. This trial enrolled 26 participants with asthma in Canada, was randomized, double-blind, and active-controlled, and included patients aged 12 years and older.

Is ciclesonide the same as any other drug?

Ciclesonide is not known to have alternative names. It is a distinct small molecule being developed by Takeda for asthma. No other names for this drug have been reported in the available clinical trial information.