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Nivolumab

Phase 2

Multiple Myeloma | Small molecule | Oncology |Atrium Therapeutics, Inc.|Last Updated: Apr 16, 2026

Success Probability
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Market & Valuation
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Trial Design
UNCONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment1
FDA Designations
No designations recorded
Clinical trial landscape

Nivolumab · 1 trial · 1 indication

Phase 2 1
NCT06523621Nivolumab in Multiple Myeloma Patients After Idecabtagene VicleucelMultiple Myeloma
ACTIVE NOT_RECRUITING1 Analytics
PHASE2ACTIVE NOT_RECRUITING
Nivolumab in Multiple Myeloma Patients After Idecabtagene Vicleucel
Multiple MyelomaUnlock trial analytics
Study Endpoints
Primary Endpoints
Depth of Response
From enrollment to best response; approximately 5 months after initiating nivolumab

Depth of response will be determined for each participant post ide-cel with adjuvant nivolumab indicating if their best overall response is a Complete Response (CR) or stringent Complete Response (sCR). The post-ide-cel disease response assessments will be calculated relative to the participant's pre-ide-cel disease assessment parameters. Responses will be determined per IMWG 2016 response criteria.

Secondary Endpoints
Progression Free Survival (PFS)
From date of ide-cel administration to date of progression or death, or censored as described; assessed for approximately 4 years
Best Overall Response
From enrollment to best response; approximately 5 months after initiating nivolumab
Duration of Response (DoR)
From date of best response to date of progression or death, or censored as described; assessed for approximately 4 years
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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Single ArmEXPERIMENTALNivolumab
Interventions
NameTypeDescription
NivolumabDRUG2 cycles of nivolumab at a dose of 480 mg given over approximately 30-minutes intravenously on Day 1 of each treatment cycle
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Eligibility Criteria
Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: 1. Written informed consent and HIPAA authorization for release of personal health information signed by the participant or his/her legally authorized representative 2. Age ≥ 18 years at the time of consent 3. ECOG Performance Status (PS) of ≤ 1 at the time of enrollment. PS mus...

Countries:United States
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Competitive Landscape -Multiple Myeloma 222 trials

Top 20 of 26 competitors

CompanyTickerTrialsLead PhaseDrugs
AbbVie, Inc.ABBV16PHASE3Pomalidomide, Dexamethasone, Venetoclax
Bristol-Myers Squibb CompanyBMY18PHASE3Iberdomide, Lenalidomide
Takeda Pharmaceutical Co. Ltd. Sponsored ADRTAK5PHASE3IGI, 10%
GSK plc Sponsored ADRGSK17PHASE3Belantamab mafodotin, Pomalidomide, Dexamethasone, Bortezomib
Johnson & JohnsonJNJ28PHASE3Bortezomib, Dexamethasone, Lenalidomide, Cilta-cel, Cyclophosphamide
Regeneron Pharmaceuticals, Inc.REGN11PHASE3Linvoseltamab, Carfilzomib, Daratumumab, Dexamethasone, Pomalidomide
Pfizer Inc.PFE11PHASE3Elranatamab, Lenalidomide
Sanofi SA Sponsored ADRSNY18PHASE3Isatuximab, Dexamethasone, Pomalidomide, Montelukast, Paracetamol / Acetaminophen
AstraZeneca PLCAZN5PHASE3AZD0120, Daratumumab, Carfilzomib, Dexamethasone, Bortezomib
Gilead Sciences, Inc.GILD3PHASE3Anitocabtagene Autoleucel, Cyclophosphamide, Fludarabine, Pomalidomide, Bortezomib
Karyopharm Therapeutics, Inc.KPTI6PHASE3Selinexor, Elotuzumab, Pomalidomide, Dexamethasone
Grifols, S.A. Sponsored ADR Class BGRFS1PHASE3Xembify
BioLineRX Ltd. Sponsored ADRBLRX1PHASE3BL-8040 /kg, G-CSF
C4 Therapeutics, Inc.CCCC3PHASE2Cemsidomide, Dexamethasone
Cellectar Biosciences, Inc.CLRB1PHASE2Iopofosine I 131 single dose, Iopofosine I 131 fractionated dose
GeoVax Labs, Inc.GOVX1PHASE2COVID-19 Vaccine, Synthetic MVA-based SARS-CoV-2 Vaccine GEO-CM04S1
Autolus Therapeutics Plc Sponsored ADRAUTL1PHASE2AUTO CAR T cell therapy
Incyte CorporationINCY2PHASE1Ruxolitinib, Lenalidomide, Methylprednisolone
Moderna, Inc.MRNA2PHASE1mRNA-2808
BeOne Medicines Ltd. Sponsored ADRONC1PHASE1Sonrotoclax, Dexamethasone, Carfilzomib, Daratumumab, Pomalidomide
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Recent Changes (Last 90 Days)
LOWMay 24, 2026NCT06523621studyFirstPostDate: changed