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RO4989991

Phase 1

Asthma | Small molecule | Respiratory |Roche Holding AG|Last Updated: Nov 2, 2016

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment24

FDA Designations

No designations recorded

Clinical trial landscape

RO4989991 · 1 trial · 1 indication

Phase 1 1
NCT01152619A Study of RO4989991 in Patients With Allergic RhinitisAsthma
COMPLETED24 Analytics
PHASE1COMPLETED
A Study of RO4989991 in Patients With Allergic Rhinitis
AsthmaUnlock trial analytics

Study Endpoints

Primary Endpoints

Assessment of the safety and tolerability of RO4989991
24 weeks

Secondary Endpoints

Assessment of pharmacokinetics
24 weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTAL -
2EXPERIMENTAL -
3PLACEBO_COMPARATOR -
4PLACEBO_COMPARATOR -

Interventions

NameTypeDescription
PlaceboDRUGSubcutaneous repeated dose
RO4989991DRUGSubcutaneous repeated dose
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites4

Inclusion Criteria: * Adult patients, 18-65 years of age, inclusively * A history of allergic rhinitis diagnosed by a physician, but otherwise healthy * A positive skin prick test to at least one standardized allergen at screening * A body mass index (BMI) between 18 and 32 kg/m2, inclusively Excl...

Countries:United States
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Frequently asked questions about RO4989991

What is RO4989991 used for?

RO4989991 is an investigational small molecule being studied for the treatment of asthma. It is being developed by Roche Holding AG (ticker: RHHBY) and is currently in Phase 1 clinical development.

What does RO4989991 target?

The specific molecular target of RO4989991 has not been disclosed in available information. It is a small molecule being investigated for its potential therapeutic effect in asthma.

Who makes RO4989991?

RO4989991 is being developed by Roche Holding AG, a multinational healthcare company. Roche's stock is traded under the ticker RHHBY on the OTC market.

What phase is RO4989991 in?

RO4989991 is in Phase 1 clinical development. It has completed one Phase 1 trial, and there are no active trials currently ongoing.

What clinical trials is RO4989991 in?

RO4989991 has been studied in one clinical trial, identified as NCT01152619. This was a Phase 1, randomized, double-blind, placebo-controlled study in patients with allergic rhinitis, conducted in the United States. The trial has been completed.

Is RO4989991 FDA approved?

RO4989991 is not FDA approved. It is an investigational drug that has completed Phase 1 clinical trials but has not yet received regulatory approval for any indication.