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PF-610, 355

Phase 2

Asthma | Small molecule | Respiratory |Pfizer, Inc.|Last Updated: Nov 1, 2010

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment42

FDA Designations

No designations recorded

Clinical trial landscape

PF-610, 355 · 1 trial · 1 indication

Phase 2 1
NCT00468975A Blinded Study To Examine The Ability Of PF-610,355 To Open The Airways In Asthmatic Patients.Asthma
COMPLETED42 Analytics
PHASE2COMPLETED
A Blinded Study To Examine The Ability Of PF-610,355 To Open The Airways In Asthmatic Patients.
AsthmaUnlock trial analytics

Study Endpoints

Primary Endpoints

Peak and Trough (24 hour post dose) FEV1.

Secondary Endpoints

Peak and trough (24 hour post dose) PEFR
FEV1 and PEFR measurements to 32 hours post dose.
Pharmacokinetics of PF-610,355 and salmeterol
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelCROSSOVER
PurposeTREATMENT

Interventions

NameTypeDescription
PF-610,355DRUG -
SalmeterolDRUG -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites6

Inclusion Criteria: * Reversible asthmatic patients (\>15% increase in FEV1 following 200ug salbutamol). * FEV1 greater than or equal to 60% predicted * Stable disease for at least the previous 3 months Exclusion Criteria: * Subjects requiring rescue medication on greater than 2 occasions in the ...

Countries:GermanySwedenUnited Kingdom
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Frequently asked questions about PF-610, 355

What is PF-610,355 used for?

PF-610,355 is an investigational small molecule being studied for the treatment of asthma. It is designed to open the airways in asthmatic patients, according to a completed Phase 2 clinical trial. The drug is being developed by Pfizer, Inc. and is not yet approved for any use.

Who makes PF-610,355?

PF-610,355 is being developed by Pfizer, Inc., a biopharmaceutical company listed on the New York Stock Exchange under the ticker symbol PFE. The drug is an investigational small molecule in Phase 2 clinical development for the treatment of asthma.

What phase is PF-610,355 in?

PF-610,355 is in Phase 2 clinical development. A Phase 2 trial has been completed, but the drug remains investigational and has not been approved by regulatory authorities. It is being studied for the treatment of asthma.

What clinical trials is PF-610,355 in?

PF-610,355 has one completed Phase 2 clinical trial, identified as NCT00468975. The study was a blinded trial examining the ability of PF-610,355 to open the airways in asthmatic patients. It enrolled 42 participants in Germany, Sweden, and the United Kingdom.

Is PF-610,355 FDA approved?

PF-610,355 is not FDA approved. It is an investigational drug in Phase 2 clinical development for asthma. A Phase 2 trial has been completed, but the drug has not yet received regulatory approval for any indication.