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IMA-026

Phase 1

Asthma | Small molecule | Respiratory |Pfizer, Inc.|Trials Updated: Jun 2, 2009

IMA-026 development status

Highest phase Phase 1
Registered trials 3 across 1 sponsor since Aug 2007

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment24

FDA Designations

No designations recorded

IMA-026 clinical trials

IMA-026 · 1 trial · 1 indication

Phase 1 1
NCT00725582Study Evaluating the Effect of IMA-026 on Allergen-Induced Late Asthma Response in Mild AsthmaAsthma
COMPLETED24 Analytics
PHASE1COMPLETED
Study Evaluating the Effect of IMA-026 on Allergen-Induced Late Asthma Response in Mild Asthma
AsthmaUnlock trial analytics

Study Endpoints

Primary Endpoints

Comparison of the maximum change in FEV1 from baseline for the LAR between IMA-026 and placebo
11 weeks

Secondary Endpoints

Treatment comparison of the hour 3 and hour 7 FEV1 AUC for the LAR; various comparisons of the methacholine PC20
11 weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
AEXPERIMENTAL -
BPLACEBO_COMPARATOR -

Interventions

NameTypeDescription
IMA-026DRUG -
PlaceboOTHER -
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Eligibility Criteria

Age Range18 Years to 60 Years
SexALL
Healthy VolunteersNo

Inclusion Criteria: 1. Healthy men and women 18 to 60 yrs with mild allergic asthma 2. only asthma med is short-acting bronchodilator used not more than twice weekly 3. FEV1 greater than 70% predicted and a demonstrated baseline late response to allergen induction Exclusion Criteria: 1. Upper res...

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Frequently asked questions about IMA-026

What is IMA-026?

IMA-026 is an investigational small molecule being developed by Pfizer, Inc. (ticker PFE) as a potential treatment for asthma. It has been studied in a Phase 1 clinical trial and is not yet approved for any indication. It belongs to the respiratory therapeutic area.

What is IMA-026 used for in asthma?

IMA-026 is being evaluated for the treatment of asthma, specifically in patients with mild asthma. A Phase 1 study assessed its effect on allergen-induced late asthma response. The drug remains investigational and has not been approved for clinical use in asthma or any other condition.

Who makes IMA-026?

IMA-026 is developed by Pfizer, Inc., which trades under the ticker symbol PFE. Pfizer sponsored the clinical research evaluating the compound in asthma. No other developer or partnership for IMA-026 is disclosed.

What phase is IMA-026 in?

IMA-026 is in Phase 1 clinical development. One Phase 1 trial has been completed, and no active trials are currently listed. The drug is investigational and has not received FDA approval for any indication.

What clinical trials is IMA-026 in?

IMA-026 has been studied in one completed Phase 1 trial, NCT00725582, titled "Study Evaluating the Effect of IMA-026 on Allergen-Induced Late Asthma Response in Mild Asthma." The trial enrolled 24 participants, was randomized, double-blind, and placebo-controlled, and included adults aged 18 years and older.