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GBT440

Phase 1

Healthy Subjects | Small molecule | Hematology |Pfizer, Inc.|Last Updated: Feb 14, 2018

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment133
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT02285088A Study of the Safety, Blood Levels and Biological Effects of GBT440 in Healthy Subjects and Subjects With Sickle Cell DiseasePHASE1 COMPLETED 133Dec 1, 2014May 1, 2017Feb 14, 2018 -
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Study Design & Arms
Interventions
NameTypeDescription
GBT440DRUGGBT440 will be administered as oral capsules
PlaceboDRUGMatching placebo will be administered as oral capsules
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