Recent Updates
Recently added Catalysts

Enbrel, Etanercept

Phase 3

Psoriasis | Unknown | Dermatology |Pfizer, Inc.|Last Updated: Mar 30, 2012

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials1
Total Enrollment421

FDA Designations

No designations recorded

Clinical trial landscape

Enbrel, Etanercept · 1 trial · 1 indication

Phase 3 1
NCT00482170Compare Perceptions and Satisfaction for Two Different Delivery Mechanisms for EtanerceptPsoriasis
COMPLETED421 Analytics
PHASE3COMPLETED
Compare Perceptions and Satisfaction for Two Different Delivery Mechanisms for Etanercept
PsoriasisUnlock trial analytics

Study Endpoints

Primary Endpoints

Participant Satisfaction With Injection Device Evaluated at Week 12 for Modified Intent-to-treat (mITT) Population
Week 12

Participant satisfaction was assessed by asking the question, "How satisfied are you with your injection device?" using a 0-10 point scale, where 0= totally dissatisfied and 10= totally satisfied.

Participant Satisfaction With Injection Device at Week 12 for Per-protocol (PP) Population
Week 12

Participant satisfaction was assessed by asking the question, "How satisfied are you with your injection device?" using a 0-10 point scale, where 0= totally dissatisfied and 10= totally satisfied.

Secondary Endpoints

Percentage of Participants Satisfied With Injection Device
Baseline, Week 4 and Week 12
Influence of Age on Participant Satisfaction With Injection Device
Week 12
Influence of Gender on Participant Satisfaction With Injection Device
Week 12
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTALArm 1: Enbrel 50 mg Prefilled Syringe
2ACTIVE_COMPARATORArm 2 Enbrel 50 mg Autoinjector

Interventions

NameTypeDescription
Enbrel (etanercept)DEVICEArm 1 = Enbrel 50 mg Prefilled Syringe twice weekly
EtanerceptDEVICEArm 2 = Enbrel 50 mg Autoinjector twice weekly
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites78

Inclusion Criteria: * Treatment of adults with moderate to severe plaque psoriasis who failed to respond to, or who have a contraindication to, or are intolerant to other systemic therapy including cyclosporine, methotrexate or PUVA * Eligible for treatment with etanercept according to Summary of P...

Countries:BelgiumDenmarkFinlandFranceGermanyGreeceHungaryItalyNetherlandsNorwaySpainSweden
Unlock Eligibility Criteria

Frequently asked questions about Enbrel, Etanercept

What is Enbrel used for?

Enbrel is used for the treatment of ankylosing spondylitis and psoriasis. It is also studied in healthy subjects for pharmacokinetic evaluation. The drug is in Phase 3 clinical development for these indications, with completed trials in ankylosing spondylitis and psoriasis.

Who makes Enbrel?

Enbrel is developed by Pfizer, Inc., which is publicly traded under the ticker symbol PFE. The company is conducting clinical trials to evaluate the drug's efficacy and safety in patients with ankylosing spondylitis and psoriasis.

What phase is Enbrel in?

Enbrel is in Phase 3 clinical development. Clinical trials have been completed for ankylosing spondylitis and psoriasis, with a total of 421 participants enrolled across studies. The drug is investigational and not yet approved for these indications.

What clinical trials is Enbrel in?

Enbrel has completed Phase 3 trials including NCT00421915 and NCT00434044 for ankylosing spondylitis, and NCT00482170 for psoriasis. A Phase 1 trial, NCT00502879, studied the drug in healthy Chinese male subjects. All trials are completed.

Is Enbrel the same as etanercept?

Yes, Enbrel is the same as etanercept. Clinical trial titles refer to etanercept as the active substance. The drug is being studied for ankylosing spondylitis and psoriasis, with completed Phase 3 trials.