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Eli Lilly and Company

LLY
Richly ValuedPharma · Commercial
FDA catalysts, PDUFA dates & pipeline intelligence
$1,179.27
▲ +7.45 · +0.64%

Financials

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52W LOW $783.8552W HIGH $1,292.65
Volume
1.39 M
Value Traded
3.68 B
Short % Float
0.89%
+3.16%Week
+5.01%1 Month
-0.22%3 Month
+26.86%6 Month
+432.5%5 Year
+37,819.33%All Time

Cash Data

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Key Stats

Market Cap
1110.11 B
EPS (TTM)
29.97
P/E Ratio
39.35
Ent. Value
1149.02 B
Total Shares
940.94 M
Float Shares
848.42 M
Insiders
9.87%
Institutions
76.28%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
BLA Submission
retatrutide
obesity, knee osteoarthritis pain, obstructive sleep apnea
BLAPeptidesEndocrine System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

LLY Catalyst Timeline

Dated clinical, regulatory and corporate events for Eli Lilly and Company

Catalyst Timeline

Dated clinical, regulatory & corporate events for Eli Lilly and Company

2673Total events
55Upcoming
1119Tier-1 (high impact)
2011 to 2040Coverage

Upcoming catalysts 2

T2Product Launch
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OnswikApproved
T3Enrollment Milestone
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BaricitinibApproved

Event history 50

▲Additional DataZepboundApprovedClinical Data
Exploratory biomarker data for Zepbound used concomitantly with Taltz in TOGETHER-PsO
moderate-to-severe plaque psoriasis and obesity or overweightsource ↗
▲Additional DataIxekizumabApprovedClinical Data
Exploratory biomarker data from TOGETHER-PsO presented at Fall Clinical 2026
moderate-to-severe plaque psoriasis and obesity or overweightsource ↗
◆Poster PresentationLebrikizumabApprovedPresentation
Lebrikizumab impact on alleviating disease severity, itch burden and quality of life in patients with moderate-to-severe atopic dermatitis: 16-week interim results from a European prospective observational study (ADtrust)
moderate-to-severe atopic dermatitissource ↗
◆Poster PresentationEloralintideApprovedPresentation
Concomitant treatment with ixekizumab and tirzepatide according to demographics and disease characteristics for patients with psoriasis and overweight or obesity: Subgroup analyses from the TOGETHER-PsO randomized trial
psoriasis and overweight or obesitysource ↗
◆Poster PresentationBaricitinibApprovedPresentation
Baricitinib provides sustained efficacy through 1.5 years and consistent safety up to a maximum of 2.5 years of treatment in adolescents with severe alopecia areata: BRAVE-AA-PEDS trial results
severe alopecia areatasource ↗
◆Poster PresentationIxekizumabApprovedPresentation
Ixekizumab plus tirzepatide reduced CV risk factors vs ixekizumab alone
psoriatic disease and obesitysource ↗
▲FDA ApprovalPirtobrutinibApprovedFDA Decision
FDA approves expanded indication for Jaypirca in previously untreated CLL/SLL
previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) with no known 17p deletionsource ↗
▲Full ResultsOrforglipronApprovedClinical Data
Post-hoc analyses of ATTAIN-1 published showing reductions in predicted 10-year type 2 diabetes and cardiovascular disease risk
Obesity or overweight with a weight-related medical problemsource ↗
▲PublicationOrforglipronApprovedPresentation
Post-hoc analyses of ATTAIN-1 published in Diabetes, Obesity and Metabolism
Obesity or overweight with a weight-related medical problemsource ↗
▲Primary Endpoint MetEBGLYSSApprovedClinical Data
ADtouch primary endpoint met: 53% vs 27% placebo achieved HF-IGA 0/1 at Week 16
moderate-to-severe hand and foot atopic dermatitissource ↗
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Past FDA Catalysts and PDUFA Decisions

How LLY actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-10-08Olumiant (baricitinib) Phase 3 data presentation Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

A93 / 100
Pipeline Score
$97.2B
Pipeline Value
$341.0B
Commercial Value
Richly Valued
Valuation Signal
165
Drugs Scored
0.1x
rNPV / MCap
Top 1%
Large Pharma
(rank 1 of 660)
Percentile Rank
Eli Lilly and Company earns an A-grade pipeline score (93/100), with $97.2B risk-adjusted pipeline value, led by Baricitinib in Diabetes Mellitus, Type 1 (Phase 3).
Commercial products (revenue basis: trailing 4 quarters of total revenue (10-K and 10-Q), to Jun 2026; product lines: last four quarters to Jun 2026 (10-K and 10-Q)) Revenue $79.7B x 4.3 = $341.0B
ProductRevenuePrior periodChange
Mounjaro$32.5B$15.7B+107.4%
Zepbound$16.9B$8.9B+91.2%
Verzenio$5.9B$5.6B+5%
Trulicity$4.2B$4.7B-10.8%
Jardiance$4.1B$3.6B+13.5%
Taltz$3.5B$3.4B+2.9%
Showing 1 of 165 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Orforglipron Small moleculeNCT07153471OsteoarthritisPhase 3 ACTIVE NOT_RECRUITING 800May 1, 2028
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Clinical Trial Results

Readouts, endpoints and source filings for every LLY program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
Taltz and Zepbound psoriasis and obesityPhase 3b2026-10-09differentially expressed proteins: 482 vs. 140; differentially expressed genes: 467 vs. 16Read MoreNew Phase 3b data on Lilly's Taltz (ixekizumab) and Zepbound (tirzepatide) advance understanding of the interconnected immune and metabolic biology in adults with psoriasis and obesityRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Jonsson PatrikOfficer (EVP & President, LLY Int'l)Sell -6,500 54,146.62 held$1,175.10 08/17/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
ORBIMED ADVISORS LLC 5.7 % (32.6 %) 309.33 M 257.90 K 8.91% ( 21.10 K)
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Shares held by hedge funds each quarter, and who bought or sold.

LLY Institutional Ownership Trends

Options Data

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Put OI
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Today vs avg
Option Volume
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Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2028-12-15
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Real-Time Option Chain

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LastVolOILastVolOI
No data available
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Competitive positioning

How LLY ranks across every disease it competes in

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See how LLY ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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LLY News

LLY
Oct 9, 2026
LLYPhases
▲ +0.6%today

New Phase 3b data on Lilly's Taltz (ixekizumab) and Zepbound (tirzepatide) advance understanding of the interconnected immune and metabolic biology in adults with psoriasis and obesity

Eli Lilly presented new data from the TOGETHER-PsO Phase 3b trial, showing that the combination of Taltz and Zepbound leads to broader biomarker changes compared to Taltz alone in patients with psoriasis and obesity. The findings suggest a significant immunometabolic relationship, supporting a more integrated treatment approach. The study highlights the potential for improved patient outcomes in managing both conditions.

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LLY
Oct 5, 2026
LLYConferences/Events

Lilly to present new data across its dermatology portfolio with 21 presentations at Fall Clinical 2026, in pursuit of advancing care for chronic skin conditions

Eli Lilly will present 21 new data presentations at the Fall Clinical Dermatology Conference 2026, focusing on its dermatology portfolio. Key highlights include findings on EBGLYSS for atopic dermatitis, Taltz and Zepbound for psoriasis and obesity, and long-term outcomes for Olumiant in alopecia areata. The data aims to enhance understanding and treatment of chronic skin conditions.

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LLY
Oct 2, 2026
LLYFDA Updates

Lilly's Jaypirca (pirtobrutinib), the first-and-only approved non-covalent BTK inhibitor, receives expanded indication from U.S. FDA for certain patients with previously untreated CLL/SLL

Eli Lilly's Jaypirca (pirtobrutinib) has received FDA approval for an expanded indication, allowing its use as a first-line treatment for adult patients with previously untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) without known 17p deletion. This decision is based on the positive results from the BRUIN CLL-313 clinical trial, which demonstrated significant improvements in progression-free survival compared to standard chemoimmunotherapy. The approval highlights Jaypirca's role in the treatment continuum for CLL/SLL.

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LLY
Oct 1, 2026
LLYPhases

Lilly's oral GLP-1, Foundayo (orforglipron), was associated with significant reductions in predicted long-term risk of type 2 diabetes and cardiovascular disease

Eli Lilly announced that its oral GLP-1 medication, Foundayo, demonstrated significant reductions in the predicted long-term risks of type 2 diabetes and cardiovascular disease in adults with obesity or overweight. The findings, derived from post-hoc analyses of the ATTAIN-1 trial, suggest that Foundayo could be a valuable treatment option, potentially reducing healthcare costs linked to obesity. The results were published in Diabetes, Obesity and Metabolism.

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LLY
Sep 30, 2026
LLYPhases

Lilly's oral GLP-1, Foundayo (orforglipron), demonstrated cardiovascular safety alongside sustained A1C reduction and weight loss in its largest and longest type 2 diabetes study

Eli Lilly's Phase 3 ACHIEVE-4 trial of Foundayo (orforglipron) showed significant cardiovascular safety and efficacy in type 2 diabetes patients. The study revealed a 16% lower risk of major adverse cardiovascular events compared to insulin glargine, alongside notable reductions in A1C and body weight. Foundayo also demonstrated a lower risk of cardiovascular and all-cause death, highlighting its potential as a treatment option.

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LLY
Sep 30, 2026
LLYPhases

New Phase 3b data show Lilly's EBGLYSS (lebrikizumab-lbkz) delivered significant and rapid improvements in skin clearance, itch, pain, and patient satisfaction in people with moderate-to-severe hand and foot atopic dermatitis

Eli Lilly's EBGLYSS (lebrikizumab-lbkz) has shown promising results in a Phase 3b study for treating moderate-to-severe hand and foot atopic dermatitis. The study reported that over 53% of patients achieved clear or almost clear skin by Week 16, with significant improvements in itch and pain relief. Additionally, nearly 80% of patients expressed satisfaction with their treatment outcomes. These findings will be presented at the EADV Congress.

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LLY
Sep 30, 2026
LLYPhases

Lilly's EloraTZP (combination of eloralintide and tirzepatide) delivered greater weight loss and A1C reduction vs. tirzepatide 15 mg in adults with obesity and type 2 diabetes

Eli Lilly announced positive results from a Phase 2b trial of EloraTZP, a combination of eloralintide and tirzepatide, showing greater weight loss and A1C reduction compared to tirzepatide alone. Participants lost an average of 54.1 lbs and lowered A1C by 2.9% over 48 weeks. Lilly plans to initiate Phase 3 trials by the end of 2026.

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LLY
Sep 29, 2026
LLYPhases

Lilly's triple agonist, retatrutide, delivered substantial weight loss and A1C reduction, underscoring its potential promise for people with obesity and type 2 diabetes

Eli Lilly announced promising results from the Phase 3 TRIUMPH-2 trial of retatrutide, a triple hormone receptor agonist, showing significant weight loss and A1C reduction in participants with obesity and type 2 diabetes. Over 80 weeks, participants lost an average of 49.6 lbs, with many no longer classified as obese. The drug also demonstrated improvements in cardiovascular risk factors, indicating its potential as a treatment option.

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LLY
Sep 29, 2026
LLYPhases

Lilly's Zepbound (tirzepatide 10 mg and 15 mg) was associated with more weight loss than Wegovy HD (semaglutide injection 7.2 mg) in a new indirect treatment comparison

Eli Lilly's Zepbound (tirzepatide) demonstrated superior weight loss compared to Wegovy HD (semaglutide) in a recent analysis. The study indicated that Zepbound 15 mg led to a 4.5% greater reduction in body weight and significantly increased the odds of achieving a 20% weight loss. These results were presented at the EASD Annual Meeting and support the efficacy of Zepbound in obesity treatment.

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LLY
Sep 29, 2026
LLYPhases

Lilly's Foundayo (orforglipron) 17.2 mg showed greater weight loss and A1C reduction than oral semaglutide 25 mg among adults with type 2 diabetes in a new indirect treatment comparison

Eli Lilly announced that Foundayo (orforglipron) 17.2 mg demonstrated significantly greater weight loss and A1C reduction compared to oral semaglutide 25 mg in adults with type 2 diabetes. This conclusion is based on an indirect treatment comparison utilizing data from the ACHIEVE-3 and PIONEER PLUS studies. The findings were presented at the EASD Annual Meeting in Milan, highlighting Foundayo's potential as a foundational therapy for managing type 2 diabetes.

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LLY
Sep 28, 2026
LLYGeneral

Lilly launches the Lilly Change the Course Commitment, aiming to address treatment gaps in diabetes and obesity in LMICs

Eli Lilly has launched the Lilly Change the Course Commitment, aiming to provide equal access to its diabetes and obesity medicines in low- and middle-income countries (LMICs) by 2040. The initiative focuses on registering innovative treatments and strengthening health systems to address significant access gaps. This commitment builds on the success of the previous Lilly 30x30 initiative, which exceeded its target of helping 30 million people by 2025.

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LLY
Sep 25, 2026
LLYFDA Updates

FDA approves Lilly's Olumiant (baricitinib) for pediatric patients 12 years of age and older with severe alopecia areata

The FDA has approved Eli Lilly's Olumiant (baricitinib) for pediatric patients aged 12 and older with severe alopecia areata. This approval is based on the BRAVE-AA-PEDS study, demonstrating significant hair regrowth and safety consistent with adult usage. The treatment offers a much-needed option for adolescents facing severe hair loss, impacting their social and personal lives.

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LLY
Sep 24, 2026
LLYFDA Updates

U.S. Food and Drug Administration (FDA) approves Lilly's Onswik™ (insulin efsitora alfa-gobe), a once-weekly basal insulin injection treatment for adults living with type 2 diabetes

Eli Lilly's Onswik (insulin efsitora alfa-gobe) has received FDA approval as a once-weekly basal insulin for adults with type 2 diabetes. This new treatment aims to simplify diabetes management by significantly reducing the number of injections required annually. The approval is based on the QWINT Phase 3 clinical trials, which showed comparable efficacy and safety to existing daily insulins. Onswik is expected to enhance patient flexibility in managing their condition.

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LLY
Sep 21, 2026
LLYGeneral

Lilly breaks ground in Houston, one of ten U.S. manufacturing sites announced since 2020

Eli Lilly has commenced construction on a new $6.5 billion manufacturing facility in Houston, Texas, aimed at producing active pharmaceutical ingredients, including Foundayo, a GLP-1 receptor agonist. This site is part of Lilly's broader initiative to reshore medicine production and is expected to create over 600 high-wage jobs. The investment also includes a partnership with San Jacinto College to develop a skilled workforce.

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LLY
Sep 18, 2026
LLYFDA Updates

U.S. FDA approves Inluriyo (imlunestrant) in combination with Verzenio (abemaciclib) for adults with ER+, HER2-, ESR1-mutated advanced or metastatic breast cancer

The U.S. FDA has approved Inluriyo (imlunestrant) in combination with Verzenio (abemaciclib) for adults with ER+, HER2-, ESR1-mutated advanced or metastatic breast cancer. This approval is based on the Phase 3 EMBER-3 trial, which demonstrated that the combination therapy significantly improves median progression-free survival. The treatment offers a new option for patients experiencing disease progression after prior endocrine therapy.

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LLY
Sep 15, 2026
LLYConferences/Events

Lilly to present new data on Foundayo, retatrutide, and eloraTZP at EASD 2026, as it strives to change the course of cardiometabolic health

Eli Lilly will present new data on its cardiometabolic health portfolio at EASD 2026, highlighting pivotal results from the TRIUMPH-2 study for retatrutide, which showed significant weight loss and A1C improvements. Additionally, findings from the ACHIEVE-4 study reaffirmed Foundayo's safety and potential cardiovascular benefits. Lilly aims to expand treatment options for diabetes and obesity.

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LLY
Sep 11, 2026
LLYGeneral

Lilly completes acquisition of AtaiBeckley to advance therapies for treatment-resistant depression and other mental health conditions

Eli Lilly has successfully completed its acquisition of AtaiBeckley Inc., a company focused on developing rapid-acting neuroplastogens for mental health conditions, particularly treatment-resistant depression. This acquisition aims to advance innovative therapies that could provide new treatment options for patients. The transaction received shareholder approval, highlighting confidence in the potential benefits of the merger.

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LLY
Sep 1, 2026
LLYConferences/Events

Lilly to participate in Morgan Stanley 24th Annual Global Healthcare Conference

Eli Lilly and Company will participate in the Morgan Stanley 24th Annual Global Healthcare Conference on September 14, 2026. Ilya Yuffa, the executive vice president, will engage in a fireside chat at 1:50 p.m. Eastern time. A live audio webcast will be available on Lilly's investor website, along with a replay for 90 days.

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LLY
Aug 31, 2026
LLYGeneral

Lilly to acquire Merida Biosciences to advance treatments for serious autoimmune and allergic diseases

Eli Lilly has announced its acquisition of Merida Biosciences for up to $2.875 billion to enhance its immunology portfolio. Merida's lead candidate, MER511, is in Phase 1 trials targeting Graves' disease and thyroid eye disease, showing promising initial results. The acquisition aims to address serious autoimmune and allergic diseases with a precision approach that selectively removes pathogenic autoantibodies.

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LLY
Aug 31, 2026
LLYPhases

New Phase 3b data on Lilly's Taltz (ixekizumab) and Zepbound (tirzepatide) used together showed improved and durable efficacy at one year in adults with psoriatic disease and obesity

Eli Lilly announced positive results from the TOGETHER-PsO and TOGETHER-PsA Phase 3b trials, demonstrating that the combination of Taltz (ixekizumab) and Zepbound (tirzepatide) maintained or improved disease activity in adults with psoriatic disease and obesity over 52 weeks. The trials showed statistically superior outcomes compared to Taltz alone, with improvements in systemic inflammation and metabolic health. No new safety concerns were reported, supporting the efficacy of this combined treatment approach.

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About Eli Lilly and Company

Indianapolis, IN 50,000 employees lilly.com
HeadquartersLILLY CORPORATE CTR, INDIANAPOLIS, IN, 46285
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