Full Press Release Details
INDIANAPOLIS , Oct. 6, 2015 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY ) will showcase results from the ixekizumab clinical development program during the 24 th European Academy of Dermatology and Venereology Congress in Copenhagen, Denmark , Oct. 7-11. Ixekizumab is the company's investigational medicine for the treatment of moderate-to-severe plaque psoriasis.
A total of 13 presentations, including a late-breaker oral presentation on Saturday, Oct. 10 , will report results on the investigational medicine's efficacy, safety and patient-reported outcomes.
"For those with moderate-to-severe psoriasis, this chronic disease can affect many facets of their daily lives, including physical and emotional well-being, professional careers and personal relationships," said David Ricks , Lilly senior vice president, and president, Lilly Bio-Medicines. "The data to be presented provide further evidence about ixekizumab's potential, if approved, to help more people achieve clear skin and improve their quality of life."
Data to be presented include: Oral Presentations: Thursday, Oct. 8, 2015 , 1:15-3:45 p.m. CEST : Session FC03, Location: B3M1-4
Saturday, Oct. 10, 2015 , 8:00-11:15 a.m. CEST : Late-Breaker Session, Location: C1M4
Oral Poster Presentation: Thursday, Oct. 8, 2015 , 11:20-11:30 a.m. CEST : Session OP01, Location: Interactive e-Poster Area
Poster Presentations: Wednesday, Oct. 7 to Sunday, Oct. 11, 2015
About ixekizumab Ixekizumab is a monoclonal antibody with high affinity and specificity that binds to and neutralizes the pro-inflammatory cytokine interleukin-17A (IL-17A). In psoriasis, IL-17A plays a major role in driving excess keratinocyte (skin cell) proliferation and activation. Ixekizumab does not bind to cytokines IL-17B, IL-17C, IL-17D, IL-17E or IL-17F. Ixekizumab is administered via subcutaneous injection (under the skin). Ixekizumab is also in clinical development for the treatment of psoriatic arthritis.
About the UNCOVER Studies The UNCOVER studies are double-blind, multicenter, Phase 3 studies evaluating more than 3,800 patients with moderate-to-severe psoriasis in 18 countries. UNCOVER-1 compared the safety and efficacy of different dosing regimens of ixekizumab to placebo after 12 weeks and 60 weeks of treatment. The UNCOVER-2 and -3 studies assigned patients to receive either placebo, etanercept (50 mg twice a week) or ixekizumab (80 mg every two or four weeks) for 12 weeks, following a 160 mg starting dose.
About Eli Lilly and Company Lilly is a global health care leader that unites caring with discovery to make life better for people around the world. We were founded more than a century ago by a man committed to creating high-quality medicines that meet real needs, and today we remain true to that mission in all our work. Across the globe, Lilly employees work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at www.lilly.com and newsroom.lilly.com/social-channels .
This press release contains forward-looking statements (as that term is defined in the Private Securities Litigation Reform Act of 1995) about ixekizumab as a potential treatment for moderate-to-severe plaque psoriasis and reflects Lilly's current belief. However, as with any pharmaceutical product, there are substantial risks and uncertainties in the process of development and commercialization. Among other things, there can be no guarantee that future study results will be similar to the results to date or that ixekizumab will receive regulatory approvals. For further discussion of these and other risks and uncertainties, see Lilly's most recent Form 10-K and Form 10-Q filings with the United States Securities and Exchange Commission. Except as required by law, Lilly undertakes no duty to update forward-looking statements to reflect events after the date of this release.
| Refer to: | Tim Coulom; [email protected] ; 317-771-2241 (media) |
| Philip Johnson; [email protected] ; 317-655-6874 (investors) |
SOURCE Eli Lilly and Company