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JNS002

Phase 1

Multiple Myeloma | Small molecule | Oncology |Johnson & Johnson|Trials Updated: Jul 4, 2013

JNS002 development status

Highest phase Phase 1
Registered trials 1 across 1 sponsor since Jun 2011

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment3

FDA Designations

No designations recorded

JNS002 clinical trials

JNS002 · 1 trial · 1 indication

Phase 1 1
NCT01371227A Study of JNS002 (Doxorubicin Hydrochloride Liposome Injection) in Relapsed or Refractory Multiple MyelomaMultiple Myeloma
COMPLETED3 Analytics
PHASE1COMPLETED
A Study of JNS002 (Doxorubicin Hydrochloride Liposome Injection) in Relapsed or Refractory Multiple Myeloma
Multiple MyelomaUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of patients with adverse events as a measure of safety and tolerability
Up to 21 days

Secondary Endpoints

Number of subjects who achieved a complete response or partial response
Up to 126 days
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
JNS002EXPERIMENTALJNS002 30 mg/m2 by intravenous infusion at a rate of = 1 mg/minute on Day 4 of each 21-day cycle.

Interventions

NameTypeDescription
JNS002DRUG30 mg/m2 by intravenous infusion at a rate of = 1 mg/minute on Day 4 of each 21-day cycle.
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Eligibility Criteria

Age Range20 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites2

Inclusion Criteria: * Patients confirmed diagnosis of multiple myeloma with evaluable disease parameters (1.Presence of M-protein in the serum and/or urine, 2.Increased plasma cells in the bone marrow or biopsy-proven plasmacytoma, 3.Presence of related organ tissue impairment) * Patients with prog...

Countries:Japan
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Competitive Landscape -Multiple Myeloma 338 trials

Frequently asked questions about JNS002

What is JNS002 used for?

JNS002 is an investigational small molecule being studied for the treatment of multiple myeloma. It is a liposomal formulation of doxorubicin hydrochloride, designed for use in patients with relapsed or refractory disease. The drug is currently in early clinical development and has not been approved by regulatory authorities.

Who makes JNS002?

JNS002 is being developed by Johnson & Johnson, a multinational pharmaceutical company traded on the New York Stock Exchange under the ticker JNJ. The company is conducting clinical research on this investigational oncology drug for multiple myeloma.

What phase is JNS002 in?

JNS002 is in Phase 1 clinical development. It is an investigational drug, meaning it has not yet received regulatory approval and is still being evaluated in clinical trials for safety and efficacy in patients with multiple myeloma.

What clinical trials is JNS002 in?

JNS002 has been studied in one completed Phase 1 clinical trial, identified by the National Clinical Trial number NCT01371227. This trial evaluated the drug in patients with relapsed or refractory multiple myeloma in Japan, enrolling a total of 3 participants.

Is JNS002 the same as doxorubicin hydrochloride liposome injection?

Yes, JNS002 is also known as doxorubicin hydrochloride liposome injection. The clinical trial for JNS002, NCT01371227, specifically evaluated this liposomal formulation of doxorubicin in patients with relapsed or refractory multiple myeloma.