Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT01788436 | A Study to Assess Learning Performance in Patients With Schizophrenia and Young and Elderly Healthy Volunteers | EARLY_PHASE1 | COMPLETED | 51 | — | — | Nov 1, 2012 | May 1, 2014 | Jun 17, 2014 | 1 | Belgium |
The cognitive data will be summarized and summary statistics calculated (including mean, standard deviation, median, minimum, and maximum values) for each experiment and participants group.
| Arm | Type | Description |
|---|---|---|
| Group 1: Patients with schizophrenia | EXPERIMENTAL | - |
| Group 2: Young healthy volunteers | ACTIVE_COMPARATOR | - |
| Group 3: Elderly healthy volunteers | EXPERIMENTAL | - |
| Name | Type | Description |
|---|---|---|
| Cognitive Test Battery 1 | BEHAVIORAL | The Cognitive Test Battery 1 comprises the following tasks: Practice with graphics tablet, pen and screen; Digit Symbol Substitution Test (DSST); Implicit Pattern/Sequence Learning Task (PLT\_Impl); Verbal Learning Test (VLT); Figure drawing; Mirror Drawing; Explicit Pattern Learning Task (PLT\_Expl); Delayed Recall and Recognition Test; and Pursuit rotor. |
| Cognitive Test Battery 2 | BEHAVIORAL | The Cognitive Test Battery 2 comprises the following tasks: Practice with graphics tablet, pen and screen; Digit Symbol Substitution Test (DSST); Implicit Learning Retention Test; Hopkins Verbal Learning Test (HVLT); Figure drawing; Mirror Drawing; Explicit Learning Retention Test; Instrumental Learning Task; Pursuit rotor; and Sensory Motor Interception Adaptation Task. |
Inclusion Criteria: * Group 1 (patients with schizophrenia): * Be a man or woman between 18 and 55 years of age, inclusive * Has a known history of schizophrenia of at least 12 months by the referring psychiatrist * Receives stable antipsychotic drug therapy (maximally 2) for at least 6 weeks prior...