Recent Updates
Recently added Catalysts

IMG-007

Phase 2

Atopic Dermatitis | Small molecule | Immunology |ImageneBio, Inc.|Last Updated: Feb 19, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedDouble-BlindPLACEBO_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment220
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT07037901A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic DermatitisPHASE2 RECRUITING 220Jun 17, 2025Oct 1, 2027Feb 19, 202623 United States, Canada
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Mean percent change from baseline in EASI at Week 20
Baseline, Week 20
Secondary Endpoints
Mean percent change from baseline in EASI at Week 16
Baseline, Week 16
Proportion of participants achieving a ≥ 75% reduction in EASI (EASI-75) at Week 16 and Week 20, respectively
Week 16, Week 20
Proportion of participants achieving a vIGA-AD score of 0 (clear) or 1 (almost clear) and a ≥ 2-point reduction from baseline at Week 16 and Week 20, respectively
Week 16, Week 20
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingQUADRUPLE
ModelCROSSOVER
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
IMG-007 dose 1EXPERIMENTALSubcutaneous injection as per protocol.
IMG-007 dose 2EXPERIMENTALSubcutaneous injection as per protocol.
IMG-007 dose 3EXPERIMENTALSubcutaneous injection as per protocol.
Placebo CrossoverPLACEBO_COMPARATORSubcutaneous placebo injection as per protocol. At crossover, IMG-007 subcutaneous injection as per protocol.
Interventions
NameTypeDescription
IMG-007DRUGParticipants will receive IMG-007 subcutaneously.
PlaceboDRUGParticipants will receive a placebo subcutaneously.
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — 74 Years
SexALL
Healthy VolunteersNo
Study Sites23

Key Inclusion Criteria: * Moderate-to-severe AD * Documented history of inadequate response or lack of tolerability to a stable regimen of one or more topical treatment before the Screening visit, or for whom topical treatments are otherwise inadvisable * Female participants who are not pregnant or...

Countries:United StatesCanada
Unlock Eligibility Criteria
Recent Changes (Last 90 Days)
LOWMay 24, 2026NCT07037901studyFirstPostDate: changed