Recent Updates
Recently added Catalysts

Humacyte Coronary Tissue Engineered Vessel

Phase 2

Coronary Artery Disease | Monoclonal antibody | Cardiovascular |Humacyte, Inc.|Last Updated: Jul 28, 2026

Target and mechanism

ModalityMonoclonal antibody

Also known as Humacyte Coronary Tissue Engineered Vessel (CTEV)

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

UNCONTROLLEDDMC
Total Trials1
Total Enrollment10

FDA Designations

No designations recorded

Clinical trial landscape

Humacyte Coronary Tissue Engineered Vessel · 1 trial · 1 indication

Phase 2 1
NCT07730528Study to Evaluate the Safety and Efficacy of Humacyte's Coronary Tissue Engineered Vessel (CTEV) in Patients With Coronary Artery Disease Requiring Coronary Artery Bypass Grafting (CABG)Coronary Artery Disease
NOT YET_RECRUITING10 Analytics
PHASE2NOT YET_RECRUITING
Study to Evaluate the Safety and Efficacy of Humacyte's Coronary Tissue Engineered Vessel (CTEV) in Patients With Coronary Artery Disease Requiring Coronary Artery Bypass Grafting (CABG)
Coronary Artery DiseaseUnlock trial analytics

Study Endpoints

Primary Endpoints

Rate of events (MACE, AE, AESI, etc.) in all participants implanted with CTEV
36 months

Secondary Endpoints

Graft patency at month 2 assessment among all implanted grafts
2 Months
Graft patency at month 6 assessments among all implanted grafts
6 months
Graft patency at month 12 assessments among all implanted grafts
12 Months
Unlock Study Endpoints

Study Design & Arms

AllocationNA
MaskingNONE
ModelSEQUENTIAL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Humacyte Coronary Tissue Engineered Vessel (CTEV)EXPERIMENTALSurgically implanted CTEV for CABG

Interventions

NameTypeDescription
Humacyte Coronary Tissue Engineered Vessel (CTEV)BIOLOGICALThe CTEV is a tissue-engineered acellular vascular conduit regulated as a biological product by the Food and Drug Administration (FDA). The CTEV has an inner diameter of 3.5 mm and with approximately 20 cm of usable length.
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo

Inclusion Criteria: 1. Age ≥18 years with the ability to provide written informed consent. 2. Planned first isolated CABG surgery for atherosclerotic coronary artery disease with a planned LIMA graft to the LAD and at least one other planned vessel bypass. 3. An RCA or LCx territory target vessel f...

Unlock Eligibility Criteria

Recent Changes (Last 90 Days)

LOWJul 28, 2026NCT07730528NEW_TRIAL: changed
LOWJul 28, 2026NCT07730528NEW_TRIAL: changed

Frequently asked questions about Humacyte Coronary Tissue Engineered Vessel

What is Humacyte Coronary Tissue Engineered Vessel used for?

Humacyte Coronary Tissue Engineered Vessel (CTEV) is an investigational therapy being studied for use in patients with coronary artery disease who require coronary artery bypass grafting (CABG). It is currently in Phase 2 clinical development and has not been approved by regulatory authorities.

Who makes Humacyte Coronary Tissue Engineered Vessel?

Humacyte Coronary Tissue Engineered Vessel is being developed by Humacyte, Inc., a biopharmaceutical company traded on the Nasdaq under the ticker symbol HUMA. The company is conducting clinical trials to evaluate the safety and efficacy of this investigational vessel for coronary artery bypass grafting.

What phase is Humacyte Coronary Tissue Engineered Vessel in?

Humacyte Coronary Tissue Engineered Vessel is in Phase 2 clinical development. It is an investigational product, meaning it has not yet been approved for commercial use. The ongoing Phase 2 trial is designed to evaluate its safety and efficacy in patients with coronary artery disease requiring CABG.

What clinical trials is Humacyte Coronary Tissue Engineered Vessel in?

Humacyte Coronary Tissue Engineered Vessel is being evaluated in a Phase 2 clinical trial registered as NCT07730528. This study is designed to assess the safety and efficacy of the vessel in patients with coronary artery disease requiring coronary artery bypass grafting. The trial is not yet recruiting and plans to enroll approximately 10 participants.

Is Humacyte Coronary Tissue Engineered Vessel the same as Humacyte Coronary Tissue Engineered Vessel (CTEV)?

Yes, Humacyte Coronary Tissue Engineered Vessel is also known as Humacyte Coronary Tissue Engineered Vessel (CTEV). The abbreviation CTEV is used interchangeably with the full name in clinical trial documentation and research contexts.