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Short Acting Beta Agonist

Phase 3

Asthma | Small molecule | Respiratory |GSK plc|Trials Updated: Apr 4, 2016

Short Acting Beta Agonist target and mechanism

ModalitySmall molecule

Also known as Short Acting Beta Agonist (SABA)

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment767

FDA Designations

No designations recorded

Short Acting Beta Agonist clinical trials

Short Acting Beta Agonist · 1 trial · 1 indication

Phase 3 1
NCT02293265Cross-sectional Study for Identification and Description of Severe Asthma PatientsAsthma
COMPLETED767 Analytics
PHASE3COMPLETED
Cross-sectional Study for Identification and Description of Severe Asthma Patients
AsthmaUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of severe asthma patients eligible for one or more biologic treatments for asthma
Day 1

Biologic treatments for asthma will include mepolizumab (anti-Interleukin \[IL\] 5), omalizumab (anti-immunoglobulin E \[IgE\]), and reslizumab (anti-IL5).

Secondary Endpoints

Mean and median frequency of planned and unplanned asthma-related healthcare resource utilization in the prior 12 months
Day 1
Mean and median Charlson Comorbidity Index score
Day 1
Mean pre-bronchodilator forced expiratory volume in 1 sec (FEV1)/forced vital capacity (FVC) ratio
Day 1
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP

Treatment Arms

ArmTypeDescription
Non-drug interventional groupOTHERAll enrolled participants will provide a blood sample, spirometry , and feedback on their severe asthma symptoms via questionnaires, and health related quality of life and burden of illness through response to self-administered questionnaires. No investigational product will be administered to participants.

Interventions

NameTypeDescription
Short Acting Beta Agonist (SABA)DRUGParticipants requiring a spirometry measurement will be administered a SABA in a metered dose inhaler (MDI) during the reversibility assessments
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Eligibility Criteria

Age Range12 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites74

Inclusion Criteria: * At least 12 years of age at study visit. * Participants eligible for enrolment and entry into the study must meet the following definition of severe asthma, which is based on the definition of severe asthma described in the European Respiratory Society/ American Thoracic Socie...

Countries:United StatesAustraliaCanadaFranceGermanyUnited Kingdom
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Frequently asked questions about Short Acting Beta Agonist

What is Short Acting Beta Agonist used for?

Short Acting Beta Agonist is used in asthma, a respiratory condition. It is a small molecule therapy developed by GSK plc. The clinical program includes a completed Phase 3 study in asthma patients aged 12 years and older. It is an investigational agent in clinical development rather than a marketed product.

Who makes Short Acting Beta Agonist?

Short Acting Beta Agonist is developed by GSK plc, which trades under the ticker GSK. GSK is the sponsor of the clinical program for this small molecule asthma therapy. The asset sits within the respiratory therapeutic area.

What phase is Short Acting Beta Agonist in?

Short Acting Beta Agonist is in Phase 3 development for asthma. One Phase 3 trial has been completed, and no trials are currently active. The completed study enrolled 767 participants. The program remains in clinical development.

What clinical trials is Short Acting Beta Agonist in?

Short Acting Beta Agonist has been studied in the Phase 3 trial NCT02293265, titled Cross-sectional Study for Identification and Description of Severe Asthma Patients. That trial is completed and enrolled 767 participants across the United States, Australia, Canada, France, Germany, and the United Kingdom.

Is Short Acting Beta Agonist the same as SABA?

Yes, Short Acting Beta Agonist is also known as SABA. SABA is the common abbreviation used for this drug name. Both terms refer to the same asthma therapy developed by GSK plc.