Recent Updates
Recently added Catalysts

FB-401

Phase 2

Atopic Dermatitis | Monoclonal antibody | Immunology |Forte Biosciences, Inc.|Last Updated: Sep 16, 2021

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedDouble-BlindPLACEBO_CONTROLLEDBiomarker
Total Trials1
Total Enrollment154
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT04504279Evaluation of FB-401 in Children, Adolescents and Adults (2 Years and Older) With Mild to Moderate Atopic DermatitisPHASE2 COMPLETED 154Oct 13, 2020Aug 19, 2021Sep 16, 202115 United States
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
EASI 50
16 weeks

The proportion of subjects with 50% improvement in Eczema Area and Severity Index (EASI) score from baseline at Week 16

Secondary Endpoints
Includes percent change in EASI
16 weeks
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
FB-401EXPERIMENTALFB-401 applied topically for 16 weeks.
PlaceboPLACEBO_COMPARATORPlacebo applied topically for 16 weeks.
Interventions
NameTypeDescription
FB-401BIOLOGICALTopical application
PlaceboBIOLOGICALVehicle
Unlock Study Design Details
Eligibility Criteria
Age Range2 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites15

Inclusion Criteria: * Male or female, ≥ 2 years of age * Clinical diagnosis of atopic dermatitis as defined by Hanifin and Rajka criteria that has been present for ≥ 3 months before the screening visit * Investigator Global Assessment (IGA) score of 2 (mild) or 3 (moderate) at Screening and Baselin...

Countries:United States
Unlock Eligibility Criteria