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GAMMA-Iridium-192 catheter

Phase 1

Coronary Artery Disease | Unknown | Cardiovascular |Cardinal Health, Inc.|Last Updated: Apr 24, 2008

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment579

FDA Designations

No designations recorded

Clinical trial landscape

GAMMA-Iridium-192 catheter · 1 trial · 1 indication

Phase 1 1
NCT00232778A Multicenter Trial of Localized Radiation Therapy to Inhibit Restenosis (GAMMA V)Coronary Artery Disease
COMPLETED579 Analytics
PHASE1COMPLETED
A Multicenter Trial of Localized Radiation Therapy to Inhibit Restenosis (GAMMA V)
Coronary Artery DiseaseUnlock trial analytics

Study Endpoints

Primary Endpoints

The primary effectiveness parameters will be late thrombosis of the target lesion at
9 months for non-stented patients and late thrombosis of the target lesion at
15 months for stented patients.
The safety criteria will include post-procedure Q-wave myocardial infarction, non-Q-wave myocardial infarction, death, need for bypass surgery, need for emergency bypass surgery,or need for repeat coronary angioplasty.
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
GAMMA-Iridium-192 catheterDEVICE -
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Eligibility Criteria

Age Range18 Years to 85 Years
SexALL
Healthy VolunteersNo

Inclusion Criteria: 1. The patient has a restenosis of \>60% (by subjective angiographic determination of the minimal luminal diameter compared to the distal reference diameter) within a native coronary artery which has previously undergone stent placement. 2. The patient has a history, signs of, o...

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Frequently asked questions about GAMMA-Iridium-192 catheter

What is GAMMA-Iridium-192 catheter used for?

GAMMA-Iridium-192 catheter is an investigational device being studied for use in coronary artery disease. It delivers localized radiation therapy to inhibit restenosis, which is the re-narrowing of arteries after treatment. The device is in Phase 1 clinical development and is not yet approved by regulatory authorities.

Who makes GAMMA-Iridium-192 catheter?

GAMMA-Iridium-192 catheter is being developed by Cardinal Health, Inc., a company traded on the New York Stock Exchange under the ticker symbol CAH. The company is conducting clinical research to evaluate the safety and effectiveness of this investigational device for coronary artery disease.

What phase is GAMMA-Iridium-192 catheter in?

GAMMA-Iridium-192 catheter is in Phase 1 clinical development. It is an investigational device and has not been approved by the FDA or other regulatory agencies. One clinical trial has been completed, and the device remains under study for the treatment of coronary artery disease.

What clinical trials is GAMMA-Iridium-192 catheter in?

GAMMA-Iridium-192 catheter has one completed clinical trial registered under NCT00232778, titled "A Multicenter Trial of Localized Radiation Therapy to Inhibit Restenosis (GAMMA V)." This Phase 1 trial enrolled 579 participants with coronary artery disease and was not randomized or double-blinded.

Is GAMMA-Iridium-192 catheter the same as GAMMA V?

GAMMA-Iridium-192 catheter is associated with the GAMMA V clinical trial, which is the study name for the trial NCT00232778. The trial evaluates the device for localized radiation therapy to inhibit restenosis in patients with coronary artery disease. The device itself is the investigational treatment being tested.