Recent Updates
Recently added Catalysts

4.0 CYPHER Sirolimus-Eluting Coronary Stent

Phase 3

Coronary Artery Disease | Unknown | Cardiovascular |Cardinal Health, Inc.|Last Updated: Dec 2, 2009

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

UNCONTROLLEDDMC
Total Trials1
Total Enrollment100

FDA Designations

No designations recorded

Clinical trial landscape

4.0 CYPHER Sirolimus-Eluting Coronary Stent · 1 trial · 1 indication

Phase 3 1
NCT00232752Study of the 4.0mm Sirolimus-Eluting Stent in the Treatment of Patients With Coronary Artery LesionsCoronary Artery Disease
COMPLETED100 Analytics
PHASE3COMPLETED
Study of the 4.0mm Sirolimus-Eluting Stent in the Treatment of Patients With Coronary Artery Lesions
Coronary Artery DiseaseUnlock trial analytics

Study Endpoints

Primary Endpoints

The primary endpoint is in-lesion late loss at 6 months post-procedure by QCA.
6 months post-procedure

Secondary Endpoints

Composite of Major Adverse Cardiac Events (MACE) defined as death, myocardial infarction (Q wave and non-Q wave), emergent bypass surgery, or repeat target lesion revascularization at 30 days and 6, 9, and 12 months, and 2, 3, 4 and 5 years post-proced
30 days and 6, 9, and 12 months, and 2, 3, 4 and 5 years post-procedure
Angiographic in-stent and in-lesion binary restenosis (³50% diameter stenosis) 6 months post-procedure by QCA.
6 months post-procedure
In-stent and in-lesion minimum lesion diameter (MLD) at 6 months post-procedure.
6 months post-procedure
Unlock Study Endpoints

Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTAL -

Interventions

NameTypeDescription
4.0 CYPHER Sirolimus-Eluting Coronary StentDEVICE4.0 CYPHER Sirolimus-Eluting Coronary Stent
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: 1. Male or non-pregnant female patients minimum 18 years of age 2. Diagnosis of angina pectoris as defined by Canadian Cardiovascular Society Classification (CCS I, II, III, IV) OR unstable angina pectoris (Braunwald Classification B\&C, I-II) OR patients with documented silent ...

Countries:United States
Unlock Eligibility Criteria

Frequently asked questions about 4.0 CYPHER Sirolimus-Eluting Coronary Stent

What is 4.0 CYPHER Sirolimus-Eluting Coronary Stent used for?

4.0 CYPHER Sirolimus-Eluting Coronary Stent is used for the treatment of coronary artery disease. It is a stent designed to be implanted in coronary artery lesions. The device is currently in Phase 3 clinical development and is being studied for its safety and effectiveness in patients with this condition.

Who makes 4.0 CYPHER Sirolimus-Eluting Coronary Stent?

4.0 CYPHER Sirolimus-Eluting Coronary Stent is developed by Cardinal Health, Inc., a company traded on the New York Stock Exchange under the ticker symbol CAH. The company is conducting clinical trials to evaluate the stent's use in patients with coronary artery disease.

What phase is 4.0 CYPHER Sirolimus-Eluting Coronary Stent in?

4.0 CYPHER Sirolimus-Eluting Coronary Stent is in Phase 3 clinical development. It is an investigational device and has not been approved by regulatory authorities. A Phase 3 clinical trial has been completed to assess its use in treating coronary artery disease.

What clinical trials is 4.0 CYPHER Sirolimus-Eluting Coronary Stent in?

4.0 CYPHER Sirolimus-Eluting Coronary Stent has one completed clinical trial, identified as NCT00232752. This Phase 3 study, titled 'Study of the 4.0mm Sirolimus-Eluting Stent in the Treatment of Patients With Coronary Artery Lesions,' enrolled 100 participants in the United States. The trial was not randomized or double-blinded and had no control group.

Is 4.0 CYPHER Sirolimus-Eluting Coronary Stent FDA approved?

4.0 CYPHER Sirolimus-Eluting Coronary Stent is not FDA approved. It is an investigational device currently in Phase 3 clinical development. A completed clinical trial has evaluated its use in coronary artery disease, but regulatory approval has not been granted.