Recent Updates
Recently added Catalysts

SYNERGY 48 mm

Phase 3

Coronary Artery Disease | Unknown | Cardiovascular |Boston Scientific Corporation|Last Updated: May 14, 2021

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment100
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT03350542A Clinical Trial to Assess the SYNERGY 48 mm Stent System for the Treatment of Atherosclerotic Lesion(s)PHASE3 COMPLETED 100Apr 12, 2018Jan 8, 2021May 14, 202115 United States, Latvia +2
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Target Lesion Failure Rate at 12-months
12-month

The primary endpoint is the 12-month Target Lesion Failure (TLF) rate, defined as any ischemia-driven revascularization of the target lesion (TLR), myocardial infarction (MI, Q-wave and non-Q-wave) related to the target vessel, or cardiac death.

Secondary Endpoints
Target Lesion Revascularization (TLR) Rate at 12 Months
12 months
Target Vessel Revascularization (TVR) Rate at 12 Months.
12 months
Target Vessel Failure (TVF) Rate at 12 Months
12 months
Unlock Study Endpoints
Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
SYNERGY 48 mmEXPERIMENTALSYNERGY 48 mm is a device/ drug combination product composed of two components, a device (coronary stent system including a platinum chromium stent platform) and a drug product (a formulation of everolimus contained in a bioabsorbable polymer coating)
Interventions
NameTypeDescription
SYNERGY 48 mmDEVICEA drug eluting coronary stent system
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites15

Clinical Inclusion Criteria * Subject must be at least 18 years of age * Subject (or legal guardian) understands the trial requirements and the treatment procedures and provides written informed consent before any trial-specific tests or procedures are performed * Subject is eligible for percutaneo...

Countries:United StatesLatviaNew ZealandUnited Kingdom
Unlock Eligibility Criteria