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BAY1003803

Phase 1

Psoriasis | Small molecule | Dermatology |Bayer AG|Last Updated: Mar 21, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindACTIVE_CONTROLLED
Total Trials1
Total Enrollment23

FDA Designations

No designations recorded

Clinical trial landscape

BAY1003803 · 1 trial · 1 indication

Phase 1 1
NCT02940002BAY1003803 Formulation Comparison in Open Psoriasis Plaque TestPsoriasis
COMPLETED23 Analytics
PHASE1COMPLETED
BAY1003803 Formulation Comparison in Open Psoriasis Plaque Test
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Study Endpoints

Primary Endpoints

Change in infiltrate thickness from day 1 to day 29 measured by sonography using 22 MHz B mode ultrasound
Day 1 to 29
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeOTHER

Treatment Arms

ArmTypeDescription
BAY1003803 0.1% lipophilic creamEXPERIMENTALBAY1003803 0.1% lipophilic cream (on plaque and healthy skin)
BAY1003803 0.1% ointmentEXPERIMENTALBAY1003803 0.1% ointment (on plaque and healthy skin)
BAY1003803 0.01% lipophilic creamEXPERIMENTALBAY1003803 0.01% lipophilic cream (on plaque and healthy skin)
BAY1003803 0.01% ointmentEXPERIMENTALBAY1003803 0.01% ointment (on plaque and healthy skin)
Clobetasol propionateACTIVE_COMPARATORClobetasol propionate ointment 0.05 % (on plaque and healthy skin)
Betamethasone/calcipotrieneACTIVE_COMPARATORBetamethasone/calcipotriene ointment 0.05 %/0.005% (on healthy skin)

Interventions

NameTypeDescription
BAY1003803DRUGSimultaneous application of 10μl on psoriasis plaque and on healthy skin for 4 weeks and evaluation of pharmacodynamic effect
Clobetasol propionateDRUGSimultaneous application of 10μl on psoriasis plaque and on healthy skin for 4 weeks and evaluation of pharmacodynamic effect
Betamethasone/calcipotrieneDRUGSimultaneous application of 10μl on healthy skin for 4 weeks and evaluation of pharmacodynamic effect
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Eligibility Criteria

Age Range18 Years to 64 Years
SexALL
Healthy VolunteersNo
Study Sites3

Inclusion Criteria: * Male and female (non-childbearing potential) volunteer with stable plaque-type psoriasis, but otherwise healthy * Age: 18-64 years Exclusion Criteria: * Severe disease within the last 4 weeks prior to the first study drug administration as determined by the investigator * An...

Countries:Germany
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Frequently asked questions about BAY1003803

What is BAY1003803 used for?

BAY1003803 is an investigational small molecule being developed for the treatment of psoriasis, a chronic skin condition. It is currently in Phase 1 clinical development and has been studied in a completed clinical trial in Germany.

Who makes BAY1003803?

BAY1003803 is being developed by Bayer AG, a multinational pharmaceutical company. Bayer's stock is traded on the OTC market under the ticker symbol BAYRY.

What phase is BAY1003803 in?

BAY1003803 is in Phase 1 clinical development. It is an investigational drug and has not yet been approved by regulatory authorities. One Phase 1 trial has been completed, and the drug is not currently in any active clinical trials.

What clinical trials is BAY1003803 in?

BAY1003803 has been studied in one completed Phase 1 clinical trial with the identifier NCT02940002. The trial, titled 'BAY1003803 Formulation Comparison in Open Psoriasis Plaque Test,' enrolled 23 participants with psoriasis in Germany.

Is BAY1003803 the same as BAY1003803?

BAY1003803 is the only name provided for this drug. No alternative names have been reported. It is a small molecule being developed by Bayer AG for the treatment of psoriasis.