Recent Updates
Recently added Catalysts

ATI-502

Phase 2

Atopic Dermatitis | Small molecule | Immunology |Aclaris Therapeutics, Inc.|Last Updated: Feb 17, 2020

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment22
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT03585296A Study of ATI-502 Topical Solution for the Treatment of Atopic DermatitisPHASE2 COMPLETED 22Jul 10, 2018Apr 25, 2019Feb 17, 20206 United States
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Number of Subjects withTreatment-Emergent Adverse Events (Safety and Tolerability)
8 weeks

Treatment emergent adverse events (TEAEs)graded on a 3 point scale of mild, moderate or severe

Unlock Study Endpoints
Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
ATI-502EXPERIMENTALATI-502 topical solution applied daily for four weeks.
Interventions
NameTypeDescription
ATI-502DRUGTopical Solution
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites6

Inclusion Criteria: 1. Male or non-pregnant, non-nursing female subjects ≥ 18 years old at the time of informed consent. 2. Subject must have diagnosis of AD. 3. Subject must have a diagnosis of moderate or severe AD for a period of ≥6 months prior to the first dose of study medication. 4. Body sur...

Countries:United States
Unlock Eligibility Criteria