Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00986037 | Assessment of the Safety of ABT-308 in Healthy Volunteers and Subjects With Asthma | PHASE1 | COMPLETED | 47 | — | — | Oct 1, 2009 | - | Nov 21, 2017 | - | — |
| Arm | Type | Description |
|---|---|---|
| IV ABT-308 in asthmatics | EXPERIMENTAL | ABT-308 single escalating doses in mild to moderate asthmatics |
| SC ABT-308 in asthmatics | EXPERIMENTAL | ABT-308 multiple SQ doses in mild to moderate asthmatics |
| IV ABT-308 in healthy volunteers | EXPERIMENTAL | ABT-308 single escalating IV doses in healthy volunteers |
| Name | Type | Description |
|---|---|---|
| ABT-308 | DRUG | Single IV doses |
| Placebo | DRUG | Single IV dose |
Inclusion Criteria: * Healthy volunteers: 1. A condition of good health based upon the results of medical history, physical examination, vital signs, laboratory profile and ECG. 2. BMI 18 to 29, inclusive. * Mild asthma patients: 1. Diagnosis of well-controlled, mild to moderate asthma by G...