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PF-00184562

Phase 1

Schizophrenia | Small molecule | Psychiatry |Pfizer, Inc.|Last Updated: Jul 25, 2006

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment18

FDA Designations

No designations recorded

Clinical trial landscape

PF-00184562 · 1 trial · 1 indication

Phase 1 1
NCT00150215A First In Human Study Of PF-00184562 In Healthy VolunteersSchizophrenia
COMPLETED18 Analytics
PHASE1COMPLETED
A First In Human Study Of PF-00184562 In Healthy Volunteers
SchizophreniaUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety and tolerability of single dose PF-00184562 as determined by: adverse event reporting, clinical laboratory results, vital signs, physical examinations, and electrocardiograms (ECGs).
Pharmacokinetic profile of PF-00184562 maximum concentration (Cmax)
Time to obtain maximum concentration (tmax), area under concentration-time curve (AUC), and terminal half-life (t1/2).
Exposure-response relationship of neuropsychometric and tolerability measures of PF-00184562 compared to olanzapine.
All measurements to be assessed over single doses.
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelCROSSOVER
PurposeTREATMENT

Interventions

NameTypeDescription
PF-00184562DRUG -
OlanzapineDRUG -
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Eligibility Criteria

Age Range18 Years to 55 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy male or female subjects of non-childbearing potential Exclusion Criteria: * Subjects with evidence or history of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, pancreatic, psychiatric, neurologic, active ...

Countries:United States
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Frequently asked questions about PF-00184562

What is PF-00184562 used for?

PF-00184562 is an investigational small molecule being developed for the treatment of schizophrenia. It is currently in Phase 1 clinical development, meaning it has not yet been approved by regulatory authorities and is still being studied for safety and tolerability in early-stage trials.

Who makes PF-00184562?

PF-00184562 is being developed by Pfizer, Inc., a biopharmaceutical company traded on the New York Stock Exchange under the ticker symbol PFE. The company is conducting early-stage clinical research on this investigational compound for schizophrenia.

What phase is PF-00184562 in?

PF-00184562 is in Phase 1 clinical development. It is an investigational drug, meaning it has not received regulatory approval and is not yet available for clinical use. The Phase 1 trial has been completed, and the drug remains in early-stage development.

What clinical trials is PF-00184562 in?

PF-00184562 has one completed clinical trial registered under NCT00150215, titled "A First In Human Study Of PF-00184562 In Healthy Volunteers." This Phase 1 study enrolled 18 participants in the United States and was a randomized, double-blind, uncontrolled trial.

Is PF-00184562 the same as any other drug?

No alternative names for PF-00184562 have been identified. The compound is known only by its developmental code name PF-00184562, and no other brand names or aliases have been reported in the available clinical trial information.