Recent Updates
Recently added Catalysts

VYD2311-SD

Phase 3

COVID-19 | Small molecule | Infectious Disease |Invivyd, Inc.|Last Updated: Jun 10, 2026

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment1,770

FDA Designations

FAST_TRACK

Clinical trial landscape

VYD2311-SD · 1 trial · 1 indication

Phase 3 1
NCT07298434Study of VYD2311 for the Prevention of COVID-19COVID-19
ACTIVE NOT_RECRUITING1,770 Analytics
PHASE3ACTIVE NOT_RECRUITING
Study of VYD2311 for the Prevention of COVID-19
COVID-19Unlock trial analytics

Study Endpoints

Primary Endpoints

RT-PCR-confirmed symptomatic COVID-19 through Day 90
90 days

Secondary Endpoints

Assessment of safety based on treatment-emergent adverse events, injection site reactions, and hypersensitivity reactions through Day 90
90 days
Serum concentrations of VYD2311 through Day 90
90 days
Incidence of ADAs against VYD2311 through Day 90
90 days
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposePREVENTION

Treatment Arms

ArmTypeDescription
VYD2311-SD (single dose)ACTIVE_COMPARATORVYD2311 administered via IM injection on Day 1, followed by placebo injection (0.9% sodium chloride \[normal saline\]) on Day 30 and Day 60
VYD2311-MD (multidose)ACTIVE_COMPARATORVYD2311 administered via IM injection on Day 1, Day 30, and Day 60
PlaceboPLACEBO_COMPARATORNormal saline administered by IM injection on Day 1, Day 30, and Day 60

Interventions

NameTypeDescription
VYD2311-SDDRUGVYD2311-SD (single-dose arm): Intramuscular injection dosing on Day 1 with VYD2311 and Intramuscular injection dosing Placebo (normal saline) on Day 30 and Day 60
VYD2311-MDDRUGVYD2311-MD (multi-dose): Intramuscular injection dosing on Day 1, Day 30, and Day 60 with VYD2311
PlaceboDRUGIntramuscular injection dosing on Day 1, Day 30, and Day 60 with Placebo (Normal Saline)
Unlock Study Design Details

Eligibility Criteria

Age Range12 Years to 100 Years
SexALL
Healthy VolunteersYes
Study Sites20

Inclusion Criteria: Participants are eligible to be included in the study only if all the following criteria apply: 1. Is an adult aged ≥18 years or an adolescent aged 12 to \<18 years weighing at least 40 kg at the time of Screening. Note: Adolescent enrollment is allowed only if permitted by the...

Countries:United States
Unlock Eligibility Criteria

Recent Changes (Last 90 Days)

MEDIUMJun 10, 2026NCT07298434Status: RECRUITING → ACTIVE_NOT_RECRUITING
MEDIUMJun 10, 2026NCT07298434Status: RECRUITING → ACTIVE_NOT_RECRUITING

Frequently asked questions about VYD2311-SD

What is VYD2311-SD used for?

VYD2311-SD is an investigational small molecule being studied for the prevention of COVID-19. It is currently in Phase 3 clinical development and has not been approved by the FDA. The drug is being evaluated in a randomized, double-blind, placebo-controlled trial.

Who makes VYD2311-SD?

VYD2311-SD is being developed by Invivyd, Inc., a biopharmaceutical company traded on the Nasdaq under the ticker symbol IVVD. The company is conducting a Phase 3 clinical trial to evaluate the drug for the prevention of COVID-19.

What phase is VYD2311-SD in?

VYD2311-SD is currently in Phase 3 clinical development. It is an investigational drug and has not been approved by the FDA. The Phase 3 trial is active but not recruiting participants, and the drug has received Fast Track designation from the FDA.

What clinical trials is VYD2311-SD in?

VYD2311-SD is being studied in a Phase 3 clinical trial with the identifier NCT07298434. This trial is titled 'Study of VYD2311 for the Prevention of COVID-19' and is enrolling 1,770 participants aged 12 years and older in the United States. The trial is randomized, double-blind, and placebo-controlled.

Is VYD2311-SD FDA approved?

No, VYD2311-SD is not FDA approved. It is an investigational drug currently in Phase 3 clinical development for the prevention of COVID-19. The FDA has granted Fast Track designation to the drug, which is intended to expedite its development and review process.