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BMS-741672

Phase 2

Neuropathic Pain | Small molecule | Pain |Bristol-Myers Squibb Company|Last Updated: Oct 12, 2015

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment50

FDA Designations

No designations recorded

Clinical trial landscape

BMS-741672 · 1 trial · 1 indication

Phase 2 1
NCT00683423BMS-741672 for Diabetic Neuropathic PainNeuropathic Pain
COMPLETED50 Analytics
PHASE2COMPLETED
BMS-741672 for Diabetic Neuropathic Pain
Neuropathic PainUnlock trial analytics

Study Endpoints

Primary Endpoints

Reduction in weekly average pain score for BMS drug vs. placebo, computed from diary scores
recorded during the last 7 days of treatment in each period

Secondary Endpoints

Other glycemic, vascular, and mechanism-based biomarkers will be measured
throughout the study
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
AEXPERIMENTAL -
BPLACEBO_COMPARATOR -

Interventions

NameTypeDescription
BMS-741672DRUGTablets, Oral, 100 mg, once daily, 3 weeks
PlaceboDRUGTablets, Oral, 0 mg, once daily, 3 weeks treatment period, 2 weeks washout, and 2 weeks follow-up
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites8

Inclusion Criteria: * Type 1 or 2 diabetics with painful, distal, symmetrical, sensory-motor neuropathy attributed to diabetes, of at least 12 months duration * Screening HbA1c of ≥ 7% and ≤ 10% * BMI ≤ 40 kg/m2 Exclusion Criteria: * Patients with clinically significant, progressive, or potential...

Countries:United States
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Frequently asked questions about BMS-741672

What is BMS-741672 used for?

BMS-741672 is an investigational small molecule being developed for the treatment of neuropathic pain, specifically diabetic neuropathic pain. It is currently in Phase 2 clinical development and has not been approved by regulatory authorities.

Who makes BMS-741672?

BMS-741672 is being developed by Bristol-Myers Squibb Company, a biopharmaceutical company traded on the New York Stock Exchange under the ticker symbol BMY.

What phase is BMS-741672 in?

BMS-741672 is in Phase 2 clinical development. It is an investigational drug and has not been approved by the FDA or any other regulatory agency. One Phase 2 trial has been completed.

What clinical trials is BMS-741672 in?

BMS-741672 has one completed clinical trial, NCT00683423, titled 'BMS-741672 for Diabetic Neuropathic Pain.' This Phase 2 study enrolled 50 participants in the United States and was placebo-controlled, randomized, and double-blind.

Is BMS-741672 FDA approved?

No, BMS-741672 is not FDA approved. It is an investigational drug currently in Phase 2 clinical development for neuropathic pain. Its safety and efficacy have not been established, and it remains under clinical investigation.