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Halneuron

Phase 2

Chemotherapy Induced Neuropathic Pain | Small molecule | Neurology |Dogwood Therapeutics, Inc.|Last Updated: May 29, 2026

Success Probability

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment240

FDA Designations

FAST_TRACK

Clinical trial landscape

Halneuron · 1 trial · 3 indications

Phase 2 1
NCT06848348Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic PainChemotherapy Induced Neuropathic Pain
RECRUITING240 Analytics
PHASE2RECRUITING
Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain
Chemotherapy Induced Neuropathic PainUnlock trial analytics

Study Endpoints

Primary Endpoints

NRS Pain
From enrollment to end of study at 4 weeks

Change from Baseline in the weekly average of daily 24-hour pain intensity scores analyzed by percentage of responders among patients treated with Halneuron compared to Placebo

Safety Assessments
From enrollment to end of study at 4 weeks

Incidence of serious adverse events (SAEs), adverse events (AEs) and Adverse Events of Special Interests (AESIs)

Secondary Endpoints

Patient Global Impression of Change (PGIC)
Enrollment to end of study at week 4
PROMIS Fatigue
Enrollment to end of study at week 4
PROMIS Sleep
Enrollment to end of study at week 4
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
PlaceboPLACEBO_COMPARATORPlacebo
HalneuronEXPERIMENTALHalneuron
Open Label ExtensionACTIVE_COMPARATORSubjects may choose to continue in an Open Label Extension (OLE) phase if they complete the randomized phase. All subjects regardless of treatment assignment in the randomized phase will receive Halneuron, during the OLE phase of the study, if offered by the clinical site.

Interventions

NameTypeDescription
HalneuronDRUGHalneuron for Subcutaneous Injection
PlaceboDRUGPlacebo for Subcutaneous Injection
Halneuron (Open Label Extension)DRUGHalneuron for Subcutaneous Injection
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites25

Inclusion Criteria: * Male or female patients aged ≥18 years. * Neuropathic pain has been present and is attributed to platinum and/or taxane chemotherapy. * Patient has received a cancer chemotherapy regimen that included taxanes and/or platinum and has no active or discernible disease progression...

Countries:United States
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Frequently asked questions about Halneuron

What is Halneuron used for?

Halneuron is an investigational small molecule being developed for the treatment of chemotherapy induced neuropathic pain, a type of nerve pain caused by cancer treatments. It is currently in Phase 2 clinical development and has not been approved by the FDA.

Who makes Halneuron?

Halneuron is being developed by Dogwood Therapeutics, Inc., a biopharmaceutical company traded on the stock exchange under the ticker symbol DWTX. The company is conducting clinical trials to evaluate the drug's safety and efficacy for chemotherapy induced neuropathic pain.

What phase is Halneuron in?

Halneuron is currently in Phase 2 clinical development. It is an investigational drug and has not received FDA approval. The drug has been granted Fast Track designation by the FDA, which is intended to expedite the development and review process for serious conditions.

What clinical trials is Halneuron in?

Halneuron is being studied in a Phase 2 clinical trial with the identifier NCT06848348. This trial is titled 'Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain' and is currently recruiting participants in the United States. The study is randomized, double-blind, and placebo-controlled, with an enrollment target of 240 participants.

Is Halneuron the same as any other drug?

Halneuron is the primary name for this investigational drug. No alternative names have been disclosed in the available information. It is being studied under the clinical trial identifier NCT06848348 for chemotherapy induced neuropathic pain.