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BAY 3670549

Phase 2

Atrial Fibrillation | Small molecule | Cardiovascular |Bayer AG|Last Updated: Jul 30, 2026

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment360

FDA Designations

No designations recorded

Clinical trial landscape

BAY 3670549 · 1 trial · 1 indication

Phase 2 1
NCT07625215A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial FibrillationAtrial Fibrillation
NOT YET_RECRUITING360 Analytics
PHASE2NOT YET_RECRUITING
A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation
Atrial FibrillationUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of Participants with conversion from atrial fibrillation (AF) to sinus rhythm (SR), sustained for ≥1 minute, within 3 hours after start of study intervention administration, and prior to use of rescue therapy or other SoC for cardioversion
Up to 3 hours after start of administration of study intervention

AF = atrial fibrillation ; SR = sinus rhythm ; SoC = Standard of Care;

Secondary Endpoints

Number of Participants who experienced Treatment Emergent Adverse Events (TEAE)s
From pre-dose* up to 48 hours after start of administration of study intervention
Time to conversion from AF to SR as defined in the primary endpoint
Up to 3 hours after start of administration of study intervention
Number of Participants in SR, at 3 hours after start of study intervention administration without prior use of rescue therapy or other SoC for cardioversion
Up to 3 hours after start of administration of study intervention
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
BAY 3670549EXPERIMENTAL -
PlaceboPLACEBO_COMPARATOR -

Interventions

NameTypeDescription
BAY 3670549DRUGintravenous (IV) treatment
PlaceboOTHERintravenous (IV) treatment
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Eligibility Criteria

Age Range18 Years to 85 Years
SexALL
Healthy VolunteersNo
Study Sites27

Inclusion Criteria: * Participant must be 18 to 85 years of age inclusive, at the time of signing the informed consent. * Participant is hemodynamically stable and does not require emergency cardioversion, as determined by the investigator. * Participant has a current episode of atrial fibrillation...

Countries:United StatesBelgiumBulgariaGermanyHungaryItalyNetherlandsPoland
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Recent Changes (Last 90 Days)

LOWJul 30, 2026NCT07625215startDate: changed
LOWJul 30, 2026NCT07625215startDate: changed
LOWJul 6, 2026NCT07625215startDate: changed
LOWJul 6, 2026NCT07625215startDate: changed

Frequently asked questions about BAY 3670549

What is BAY 3670549 used for?

BAY 3670549 is an investigational small molecule being developed for the treatment of atrial fibrillation, a cardiovascular condition characterized by an irregular and often rapid heart rate. It is currently in Phase 2 clinical development and has not been approved by regulatory authorities.

What does BAY 3670549 target?

The specific molecular target of BAY 3670549 has not been disclosed in available information. It is a small molecule being studied for its efficacy and safety in patients with atrial fibrillation, but its mechanism of action is not publicly detailed.

Who makes BAY 3670549?

BAY 3670549 is being developed by Bayer AG, a multinational pharmaceutical company. Bayer's stock is traded over-the-counter under the ticker symbol BAYRY.

What phase is BAY 3670549 in?

BAY 3670549 is in Phase 2 clinical development. It is an investigational drug, meaning it has not been approved by the FDA or other regulatory agencies and is still undergoing clinical trials to evaluate its safety and effectiveness.

What clinical trials is BAY 3670549 in?

BAY 3670549 is being studied in a Phase 2 clinical trial with the identifier NCT07625215. This randomized, double-blind, placebo-controlled study is designed to evaluate the drug's efficacy and safety in approximately 360 patients with atrial fibrillation. The trial is not yet recruiting participants.