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Cardio Diagnostics Holdings Inc.

CDIOFDA catalysts, PDUFA dates & pipeline intelligence
$1.7
▼ -0.02 · -1.16%

Financials

Last updated
Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
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D/E Ratio
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Quarterly Cash
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52W LOW $0.9752W HIGH $7.91
Volume
2.53 K
Value Traded
26.76 K
Short % Float
0.1%
Days to Cover
1.0
-0.87%Week
-9.97%1 Month
+9.29%3 Month
-0.87%6 Month
-99.45%5 Year
-99.45%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
5.03 M
EPS (TTM)
-2.19
P/E Ratio
-
Ent. Value
-555.60 K
Total Shares
2.96 M
Float Shares
2.83 M
Insiders
4.34%
Institutions
6.52%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

CDIO Catalyst Timeline

Dated clinical, regulatory and corporate events for Cardio Diagnostics Holdings Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Cardio Diagnostics Holdings Inc.

6Total events
1Upcoming
0Tier-1 (high impact)
2026 to 2026Coverage

Upcoming catalysts 1

TBD
T2Other Regulator Milestone
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Event history 5

●R&D DayPresentation
Cardio Diagnostics to host investor conference call
▲Manufacturing MilestoneCMC / Inspection
Launch of in-house CLIA-certified laboratory in Iowa City
▲Other Regulator MilestoneEx-US Regulatory
Secured out-of-state licenses from California, Maryland, Rhode Island, and Pennsylvania
◆R&D DayPresentation
Investor conference call scheduled
▲Other Regulator MilestoneEx-US Regulatory
Received CLIA license after inspection with no deficiencies
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How CDIO actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
-Example Drug Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

No drug pipeline

Cardio Diagnostics Holdings Inc. is a diagnostics company. The clinical trials it takes part in test other companies' drugs, so it has no drug pipeline of its own to score.

Clinical Trial Results

Readouts, endpoints and source filings for every CDIO program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
Example Drug Example indication for clinical evaluationPhase 32025-12-01The study met its primary endpoint demonstrating statistically significant improvement.Read MorePhase 3 Study Results AnnouncementRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Fung Peter KDirectorGrant/Award 2,854 12,367 held$2.19 06/30/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
No hedge fund reported a 13F position in CDIO for Q2 2026.
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

CDIO Institutional Ownership Trends

CDIO Short Interest

Shares sold short, counted twice a month.

0.1%
Short % of Float
of tradable shares sold short
3.0K
Shares Sold Short
+193.6% vs prior count
1.0 Low
Days to Cover
trading days of normal volume to buy every short share back
31.9K
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Live calls and puts by strike: last price, volume and open interest for every expiry.
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How CDIO ranks across every disease it competes in

Competitive Position is a premium feature
See how CDIO ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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CDIO News

CDIO
Aug 26, 2026
CDIOGeneral

Cardio Diagnostics Report Identifies Growing Rural Cardiovascular Care Gap Amid Ongoing Workforce Shortages and Access Challenges

Cardio Diagnostics has published a new rural health report focusing on cardiovascular care. The report emphasizes the growing gap in healthcare access in rural areas, particularly due to workforce shortages. It aims to raise awareness and stimulate discussions on improving cardiovascular care in these underserved regions.

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CDIO
Aug 18, 2026
CDIOGeneral

Cardio Diagnostics Begins In-House Test Processing at Its New High Complexity CLIA-Certified Laboratory in Iowa City

Cardio Diagnostics has officially launched its in-house, high-complexity CLIA-certified laboratory located in Iowa City, Iowa. This facility is expected to enhance the company's operational capabilities and improve efficiency in test processing. The CLIA certification signifies that the laboratory meets high standards for clinical testing.

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CDIO
Aug 5, 2026
CDIOConferences/Events

Cardio Diagnostics Holdings, Inc. to Host Investor Call on Thursday, August 20, 2026

Cardio Diagnostics Holdings, Inc. has announced an upcoming investor conference call scheduled for August 20, 2026, at 3 p.m. Central Time. This event aims to engage with investors and provide updates on the company's progress and future plans. Such calls are typically intended to foster transparency and investor relations.

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CDIO
Jun 24, 2026
CDIOGeneral
▼ -7.7%on this news

Atlas Healthcare Physicians to Cover Cardio Diagnostics’ Precision Cardiovascular Medicine Tests Across Its Network

Atlas Healthcare Physicians will cover Cardio Diagnostics' precision cardiovascular medicine tests across its network. This partnership aims to enhance patient access to advanced cardiovascular diagnostics. The collaboration is expected to improve the quality of care provided to patients within the Atlas network.

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CDIO
Feb 17, 2026
CDIOConferences/Events
▼ -6.3%on this news· ran to +127% by day 3

Cardio Diagnostics Holdings, Inc. to Host Investor Call on Wednesday, February 18, 2026

Cardio Diagnostics Holdings, Inc. will host an investor call on February 18, 2026, to discuss its precision molecular approach to cardiovascular disease. The call will cover updates on its tests, Epi+Gen CHD™ and PrecisionCHD™, along with recent clinical data and growth initiatives. Participants can join via telephone or webcast.

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CDIO
Feb 10, 2026
CDIOConferences/Events

Leading the Next Frontier in Precision Cardiovascular Medicine 2026 NASDAQ: CDIO 1 Certain statements and information included in this presentation constitute "forward - looking statements" within the meaning of the Priv

Cardio Diagnostics Holdings, Inc. is at the forefront of precision cardiovascular medicine, showcasing its innovative solutions powered by epigenetics and artificial intelligence. The company aims to enhance early detection and prevention of cardiovascular diseases, presenting a comprehensive growth strategy with a robust intellectual property portfolio. With a significant total addressable market and a leadership team experienced in diagnostics and AI, Cardio Diagnostics is positioned for growth amidst the ongoing challenges of cardiovascular health. The potential future impact includes not only improved patient outcomes but also a reduction in healthcare costs associated with heart diseases.

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CDIO
May 8, 2025
CDIOGeneral
▼ -47.1%on this news

Cardio DIAGNOSTICS HoldingS, INC. ANNOUNCES 1-for-30 reverse stock split

Cardio Diagnostics Holdings, Inc. has announced a 1-for-30 reverse stock split of its common stock, effective from May 13, 2025. This action comes as part of the company's strategy to regain compliance with Nasdaq's minimum bid price requirements. Following the split, the number of outstanding shares will decrease significantly, from approximately 52 million to about 1.7 million shares. While this move could stabilize the stock price, it also reflects underlying financial pressures within the company.

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CDIO
Feb 21, 2025
CDIOGeneral
▲ +7.1%on this news

COMPANY UPDATE Revolutionizing Cardiovascular Medicine With Epigenetics and AI Certain statements and information included in this presentation constitute "forward - looking statements" within the meaning of t he Private

Cardio Diagnostics Holdings Inc. has announced key developments aimed at revolutionizing cardiovascular medicine through the integration of epigenetics and artificial intelligence. The company emphasizes the significance of forward-looking statements in their approach, highlighting a commitment to innovation within the sector. With these advancements, the company positions itself as a leader in combining cutting-edge technology with healthcare solutions.

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CDIO
Apr 2, 2024
CDIOGeneral
▼ -25.9%on this news

COMPANY UPDATE Revolutionizing Cardiovascular Medicine With Epigenetics and AI MARCH 2024 Certain statements and information included in this presentation constitute "forward - looking statements" within the meaning of t

The recent company update highlights advancements in cardiovascular medicine through the integration of epigenetics and artificial intelligence. The presentation conveys a commitment to innovative medical solutions that may enhance treatment options. Additionally, forward-looking statements imply potential developments on the horizon, positioning the company favorably within the biopharma sector.

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CDIO
Dec 6, 2023
CDIOGeneral

Cardio Diagnostics Holdings, Inc. Regains Nasdaq Minimum Bid Price Requirement CHICAGO

Cardio Diagnostics Holdings, Inc. has announced that it has regained compliance with Nasdaq's minimum bid price requirement. Following a previous notification of non-compliance, the company successfully maintained a closing bid price of $1.00 or higher for ten consecutive business days. As a result, Nasdaq has confirmed that Cardio Diagnostics can continue its listing on the Nasdaq Capital Market, categorizing the matter as closed.

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CDIO
Mar 8, 2023
CDIOGeneral
▼ -8%on this news· ran to -30% by day 3

Cardio Diagnostics Holdings, Inc Announces Financing Agreement with Yorkville Advisors Global, LP of up to $11.2 Million CHICAGO, IL

Cardio Diagnostics Holdings, Inc. has announced a financing agreement with Yorkville Advisors Global, LP for up to $11.2 million. The Company will issue convertible debentures, with the initial closing providing $4.5 million. These funds are intended to accelerate the adoption of their PrecisionCHD and Epi+Gen CHD clinical tests and support further development of new tests. The CEO highlighted the potential impact of this investment on enhancing heart disease prevention and early detection efforts.

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CDIO
Oct 31, 2022
CDIOGeneral
▼ -10.4%on this news· ran to -39% by day 3

shall have the meanings ascribed to them in the Current Report on Form 8-K (the "Form 8-K")filed with the Securities and Exchange Commission (the "SEC") on

UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL Capitalized terms used but not defined in this Exhibit 99.1 shall have the meanings ascribed to them in the Current Report on Form 8-K (the "Form 8-K")filed with the Securities and Exchange Commission (the "SEC") on October 31,

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CDIO
Sep 22, 2022
CDIOGeneral

Mana Capital Acquisition Corp. Announces Intention to Further Extend Period to Consummate Initial Business Combination Dover, DE

Mana Capital Acquisition Corp. Announces Intention Further Extend Period to Consummate Initial Business Dover, DE, September 22, 2022-Mana Capital Acquisition Corp. (Nasdaq: MAAQU; MAAQ; MAAQW; MAAQR) (the "Company" or "Mana Capital") today announced that its Board of Directo

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CDIO
Sep 21, 2022
CDIOGeneral

Cardio Diagnostics Announces Issuance of U.S. Patent for Compositions and Methods for Detecting Predisposition to Cardiovascular Disease CHICAGO, Ill - Cardio Diagnostics, Inc. ( Cardio Diagnostics or the Company ), a pi

Diagnostics Announces Issuance of U.S. Patent for and Methods for Detecting Predisposition to Cardiovascular Disease CHICAGO, Ill - Cardio Diagnostics, Inc. ("Cardio Diagnostics" or the "Company"), a pioneering precision cardiovascular testing company, today announced that th

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CDIO
Aug 26, 2022
CDIOConferences/Events

Transforming Cardiovascular Cardiovascular Health Through Our AI - Driven Integrated Genetic - Epigenetic Epigenetic Engine INVESTOR PRESENTATION August 2022 MANA CAPITAL Acquisition Corp. Disclaimer General This present

Transforming Cardiovascular Cardiovascular Health Through Our AI - Driven Integrated Genetic - Epigenetic Epigenetic Engine INVESTOR PRESENTATION August 2022 MANA CAPITAL Acquisition Corp. Disclaimer General This presentation is for informational purposes and only to assist in e

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CDIO
Aug 23, 2022
CDIOGeneral

Mana Capital Acquisition Corp. Announces Intention to Extend Period to Consummate Initial Business Combination Dover, DE

Mana Capital Acquisition Corp. Announces Intention Extend Period to Consummate Initial Business Combination Dover, DE, August 23, 2022-Mana Capital Acquisition Corp. (Nasdaq: MAAQU; MAAQ; MAAQW; MAAQR) (the "Company" or "Mana Capital") today announced that its Board of Direct

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CDIO
May 31, 2022
CDIOGeneral

Mana Capital Acquisition Corp. and Cardio Diagnostics, Inc. Announce Definitive Business Combination Agreement to Create Publicly Listed Company Set to Transform Cardiovascular Disease Through Epigenetics Cardio Diagnost

Capital Acquisition Corp. and Cardio Diagnostics, Inc. Definitive Business Combination Agreement to Create Listed Company Set to Transform Cardiovascular Disease Cardio Diagnostics, Inc. has pioneered a proprietary artificial intelligence-driven Integrated Genetic-Epigenetic E

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CDIO
Jan 14, 2022
CDIOGeneral

Mana Capital Acquisition Corp. Announces the Separate Trading of its Common Stock, Warrants and Rights, Commencing

Mana Capital Acquisition Corp. Announces the Separate Trading of its Common Stock, Warrants and Rights, Commencing Dover, DE - January 12, 2022 - Mana Capital Acquisition Corp. (Nasdaq: MAAQU) ("Mana" or the "Company"), today announced that, commencing January 14, 2022, hold

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CDIO
Nov 26, 2021
CDIOGeneral

MANA CAPITAL ACQUISITION CORP. BALANCE SHEET Actual as of

MANA CAPITAL ACQUISITION CORP. Actual as of November 26, 2021 Pro Forma Adjustments As Adjusted (Unaudited) (Unaudited) ASSETS Current Assets Cash $ 887,872 $ (60,000 ) $ 827,872 Prepaid Expenses - short term 199,725 - 19

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CDIO
Nov 26, 2021
CDIOGeneral

INDEX TO FINANCIAL STATEMENT Page Audited Financial Statement of Mana Capital Acquisition Corp.: Report of Independent Registered Public Accounting Firm F-2 Balance Sheet as of

Page Audited Financial Statement of Mana Capital Acquisition Corp.: Report of Independent Registered Public Accounting Firm F-2 Balance Sheet as of November 26, 2021 F-3 Notes to Financial Statement F-4 REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING To the Shareholders an

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About Cardio Diagnostics Holdings Inc.

Chicago, IL 17 employees cdio.ai
Headquarters311 W. SUPERIOR STREET, CHICAGO, IL, 60645
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