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AtriCure Bipolar System

Phase 3

Atrial Fibrillation | Unknown | Cardiovascular |AtriCure, Inc.|Last Updated: Mar 29, 2013

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDDMC
Total Trials1
Total Enrollment55

FDA Designations

No designations recorded

Clinical trial landscape

AtriCure Bipolar System · 1 trial · 1 indication

Phase 3 1
NCT00560885AtriCure Bipolar Radiofrequency Ablation of Permanent Atrial FibrillationAtrial Fibrillation
COMPLETED55 Analytics
PHASE3COMPLETED
AtriCure Bipolar Radiofrequency Ablation of Permanent Atrial Fibrillation
Atrial FibrillationUnlock trial analytics

Study Endpoints

Primary Endpoints

Percent of Patients Free From AF and Off Class I and III Anti-arrhythmic Drugs as Determined by Holter Monitoring at 6 Months.
6 Months Post Procedure
Composite Acute Major Adverse Event Rate, Within 30 Days Post-procedure or Hospital Discharge
30 days Post Procedure

Major Adverse Events consist of Death within 30 days or beyond 30 days if considered device related, Excessive Bleeding, Stroke, TIA or MI. A clinic visist was performed at 30 days to fully assess the patient for adverse events.

Secondary Endpoints

Percent of Patients Free From AF, Independent of Antiarrhythmic Drug Status as Determined by Holter Monitoring at 6 Months.
6 Months Post Procedure
Composite 6-month Post-procedure Major Adverse Event Rate.
6 Months Post Procedure
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
AtriCure Bipolar SystemEXPERIMENTALThe AtriCure Synergy Bipolar Ablation system is used to create lesions outlined in the Maze IV procedure during a concomitant open cardiac surgical procedure.

Interventions

NameTypeDescription
AtriCure Bipolar SystemDEVICESurgical bipolar radiofrequency ablation using the AtriCure Bipolar System
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites9

Inclusion Criteria: 1. Subject is greater than or equal to 18 years of age 2. Subject has history of permanent atrial fibrillation as defined by the ACC/AHA/ESC Guidelines 3. Subject is scheduled to undergo elective on-pump cardiac surgical procedure(s) for one or more of the following: * Mitra...

Countries:United States
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Frequently asked questions about AtriCure Bipolar System

What is AtriCure Bipolar System used for?

AtriCure Bipolar System is used for the treatment of atrial fibrillation, a condition characterized by irregular and often rapid heart rate. It is a surgical device designed for use in cardiac ablation procedures to treat this arrhythmia. The system is currently in clinical development for this indication.

Who makes AtriCure Bipolar System?

AtriCure Bipolar System is developed by AtriCure, Inc., a company publicly traded under the ticker symbol ATRC. The company is focused on surgical ablation technologies for the treatment of atrial fibrillation and related conditions.

What phase is AtriCure Bipolar System in?

AtriCure Bipolar System is in Phase 3 clinical development. It is an investigational device and has not yet been approved by regulatory authorities. The Phase 3 trial has been completed, and the device is not currently in active clinical trials.

What clinical trials is AtriCure Bipolar System in?

AtriCure Bipolar System has one completed Phase 3 clinical trial, identified by the identifier NCT00560885. This trial, titled 'AtriCure Bipolar Radiofrequency Ablation of Permanent Atrial Fibrillation,' enrolled 55 participants in the United States. The trial was uncontrolled and not randomized or double-blinded.

Is AtriCure Bipolar System the same as AtriCure Bipolar Radiofrequency Ablation?

AtriCure Bipolar System is associated with the AtriCure Bipolar Radiofrequency Ablation procedure, as indicated by the clinical trial title. The system uses bipolar radiofrequency energy for ablation, but the specific product name is AtriCure Bipolar System.