Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT01545310 | A Positron Emission Tomography Study of SLV354 in Healthy Subjects and Subjects With Schizophrenia | PHASE1 | COMPLETED | 18 | — | — | May 1, 2011 | Jul 1, 2012 | Sep 18, 2012 | 1 | United States |
5-HT6 receptor occupancy and the relationship between SLV354 plasma concentrations and receptor occupancy
| Arm | Type | Description |
|---|---|---|
| Group 1 (healthy), Group 2 (schizophrenia) | EXPERIMENTAL | - |
| Name | Type | Description |
|---|---|---|
| SLV354 | DRUG | One dose of ABT-354 |
Inclusion Criteria 1. Male, age between 18 and 55 years, inclusive. 2. Body Mass Index 18 to 30 (healthy) and 18 to 38 (schizophrenia). 3. A condition of general good physical health. 4. Schizophrenia subjects must have a diagnosis of schizophrenia based on Diagnostic and Statistical Manual of Ment...